Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Ian Paterson inquest opens into 74th former patient death

A coroner has opened a 74th inquest into a former patient of jailed surgeon Ian Paterson, whose care remains under scrutiny.

By Dr. Revathy Mohan V.R., MBBS · 1 day ago · 5 min read

Oncology·PNAS

Methionine Restriction Blocks EZH2 to Trigger Pyroptosis in Prostate Cancer

Methionine restriction and EZH2 inhibition triggered GSDMD-dependent pyroptosis in prostate cancer models, offering a metabolic-epigenetic target strategy.

1 day ago

Oncology·NICE

PROACTIF Registry Tracks Y-90 Glass Microspheres in French Liver Cancer Care

France’s PROACTIF registry is following real-world use of Y-90 glass microspheres in HCC, iCC, and metastatic colorectal cancer,…

1 day ago

Oncology·NICE

NICE approves advanced anal cancer treatment for hundreds of patients

NICE has approved a life-extending treatment for advanced anal cancer, opening access to a therapy expected to benefit…

1 day ago

Oncology·BMJ Open

Active surveillance after nCRT for oesophageal cancer faces hospital-level barriers

A Dutch qualitative study examined how hospitals can implement active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer and…

1 day ago

Oncology·JCO

Nutritional care audit in Senegal oncology services draws attention to cancer support gaps

A multicenter audit in Senegal examines nutritional care practices across oncology services, a key support domain in cancer…

1 day ago

Oncology·ScienceDaily

Bioengineered chewing gum cuts oral HPV levels in cancer samples

A lab-tested chewing gum cut oral HPV by up to 93% and nearly eliminated two cancer-linked bacteria while…

1 day ago

Oncology·Nature

High glycemic index linked to higher multiple myeloma odds in Iranian study

An Iranian case-control study found higher dietary glycemic index was linked to greater multiple myeloma odds, while glycemic…

1 day ago

Oncology·ESMO Open

Breast Cancer Pharmacoprevention Remains Underused Despite Strong Evidence

Tamoxifen, raloxifene, and aromatase inhibitors reduce hormone receptor-positive breast cancer risk, but uptake remains limited by toxicity and…

1 day ago

Oncology·Br J Cancer

PORTEC-4a: Molecular-Guided Adjuvant Therapy Cuts Toxicity in Endometrial Cancer

PORTEC-4a found molecular-guided adjuvant treatment in high-intermediate risk endometrial cancer lowered mild toxicity while preserving quality of life.

1 day ago

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.