Molecular Biology

Clinical evidence, research, and medical intelligence in Molecular Biology.

FASN Binds mRNAs and Lowers Translational Efficiency in Human Cells

A bioRxiv preprint maps FASN-RNA binding sites in human cells and links FASN depletion to reduced translational efficiency of associated mRNAs.

By Dr. A. Nikhil Krishnan, MBBS · 4 days ago · 5 min read

Molecular Biology·bioRxiv

XL-MS Framework Quantifies Protein-RNA Contacts in TDP-43 and FOX1

A new UV cross-linking mass spectrometry workflow combines detection and quantification of protein-RNA contacts in TDP-43 and FOX1…

Oct 28, 2026

Molecular Biology·bioRxiv

RhoBAST-FLIM improves live-cell RNA imaging with lifetime contrast

RhoBAST-FLIM uses fluorescence lifetime differences to sharpen live-cell RNA imaging and support super-resolution microscopy with lower depletion power.

Oct 26, 2026

Molecular Biology·bioRxiv

Fluorescent Biosensors Extend Cryogenic Correlative Microscopy

Researchers adapted fluorescent biosensors for cryogenic correlative light and electron microscopy to map calcium, pH, and osmotic stress…

Oct 26, 2026

Molecular Biology·PNAS

DNA Looping Controls gal Transcription by Blocking the Initial Complex

PNAS study shows that DNA looping, not simple operator binding, is required to repress gal transcription by blocking…

Oct 26, 2026

Molecular Biology·bioRxiv

USP18 N-terminal truncation reshapes muscle differentiation in early myogenesis

A preprint finds the short USP18 isoform has distinct stability, localization, and protein partners, and may promote early…

Oct 25, 2026

Molecular Biology·PNAS

Honeybee gene networks reorganize during nurse-to-forager transition

PNAS analysis shows honeybee behavioral maturation follows network-level transcriptomic reorganization, with polarized gene states and module-specific antagonism.

Oct 24, 2026

Molecular Biology·PNAS