Immunology

Clinical evidence, research, and medical intelligence in Immunology.

IL-1 receptor remodeling differs in asthma and rheumatoid arthritis

Flow cytometry found distinct IL-1R1 and IL-1R2 co-expression patterns in asthma and rheumatoid arthritis, with exploratory RA biomarker performance.

Machine learning identified a cfDNA fragmentomic signature of DNase1L3 impairment, outperforming genotype imputation and working with low fragment…

A VA cohort study found TNF inhibitor therapy raised absolute lymphocyte counts and those increases tracked with lower…

Human studies suggest gut microbiota can influence vaccine responses, but clinical trials remain inconsistent and causality is unproven.

A Frontiers in Immunology review examines how host enzymes, trafficking and pathogen adaptations reshape PAMPs before innate receptors…

A Frontiers in Immunology review argues that T cell longevity depends on TCF1-centered stemness, with CD4 and CD8…

Two patients with antisynthetase syndrome developed malignancy-linked flares, raising concern that cancer risk may be underestimated in selected…

Nature Immunology corrected source data and figure panels for an IGHG1 variant paper after labeling, organizational, and dataset…

Chronic infection reshapes CD8+ T cell repertoires over time, with shared early motifs giving way to divergent dominant…

Large EHR and genetic analyses show type 2 inflammatory diseases cluster in a network, with chronic sinusitis and…

Immunology

Clinical evidence, research, and medical intelligence in Immunology.

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