Genetics

Clinical evidence, research, and medical intelligence in Genetics.

Indirect Genetic Effects in ADHD and ASD Traits Across Development

Twin and trio analyses in 7,259 offspring found ADHD and ASD polygenic scores mainly tracked direct genetic effects, with limited indirect effects.

By Dr. A. Nikhil Krishnan, MBBS · 1 min ago · 6 min read

Genetics·Nature

AAV Gene Therapy IND Submissions Surged Over 30 Years, FDA Review Finds

FDA analysis of AAV gene therapy IND submissions from 1995 to 2025 finds rapid growth and recurring reasons…

4 hrs ago

Genetics·PLOS Med

Virus-like particles boost gene editing in pig and chicken models

Virus-like particles delivered Cre and CRISPR tools efficiently in pig and chicken models, spanning cells, organoids, oocytes, and…

14 hrs ago

Genetics·Cancer Cell

Molecular Engineering Boosts Zinc Finger Nuclease Genome Editing Efficiency

Cell Press reports molecular engineering of zinc finger nucleases improves genome editing efficiency in cells, with implications for…

24 hrs ago

Genetics·WHO

Africa gene editing governance review calls for pan-continental framework

A policy review proposes a phased African gene editing governance model built on regional oversight, national law, data…

1 day ago

Genetics·bioRxiv

Human 5S rDNA arrays show zoned methylation tied to chromatin architecture

Long-read sequencing maps complete human 5S rDNA arrays, revealing zone-specific methylation states and chromatin accessibility differences across units.

1 day ago

Genetics·Nat Rev Onc

Count-based single-cell eQTL models boost power in large cohorts

jaxQTL uses count-based modeling to improve single-cell eQTL discovery, increasing eGenes and prioritizing distal, cell-type-specific regulatory signals.

2 days ago

Genetics·ScienceDaily