Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Extracellular Vesicles Shape Liver Susceptibility to Colorectal Cancer Spread

Gut review examines how extracellular vesicles may prime the liver for colorectal cancer metastasis and why that matters for advanced disease.

By Dr. Revathy Mohan V.R., MBBS · 14 hrs ago · 4 min read

Oncology·Gut

Gastric Cancer Peritoneal Metastasis Resistance Tied to CAF-Macrophage Crosstalk

Single-cell profiling of gastric cancer peritoneal metastasis linked CAF-macrophage signaling through complement C3 to resistance to sintilimab-based therapy.

14 hrs ago

Oncology·PLOS Med

UHRF1 Linked to Worse Survival in Adult T-Cell Leukemia-Lymphoma

High UHRF1 expression in ATLL tissue tracked with poorer survival, and knockdown slowed cell growth while shifting apoptosis…

15 hrs ago

Oncology·Front Immunol

HAX1 links lung adenocarcinoma metastasis to brain and lymph node spread

Single-cell and clinical analyses tie HAX1 to lung adenocarcinoma progression, lymph node spread, brain metastasis, and cell-cycle signaling.

17 hrs ago

Oncology·Front Immunol

Melanoma anti-PD-1 adjuvant therapy linked to immune signatures and relapse risk

Deep blood immune profiling in resected stage III melanoma linked distinct dendritic and monocyte signatures to recurrence and…

17 hrs ago

Oncology·Front Immunol

PARD6B emerges as a context-dependent ovarian cancer dependency

Integrated genomic and tissue-resolved analyses identify PARD6B as a recurrent proliferative dependency in high-grade serous ovarian cancer.

17 hrs ago

Oncology·Front Immunol

CAR T Hematotoxicity Linked to Monocyte and Macrophage Inflammation

A Frontiers review links monocyte and macrophage activation to CAR T-associated hematotoxicity, marrow suppression, and translational biomarker targets.

17 hrs ago

Oncology·NICE