Pharmacology

Trials, guidelines and clinical evidence across Pharmacology.

PLOS ONE flags data concerns in Mas receptor antibody papers

PLOS ONE editors raised concerns about figures in two Mas receptor antibody studies, signaling unresolved questions about data reliability.

A scoping review of 73 papers maps the scientific, regulatory, economic, and implementation barriers that slow drug repurposing…

Proteomics data show aging, HIV status, and sex reshape antiretroviral disposition pathways in rectosigmoid tissue and PBMCs.

DailyMed’s updated Solu-Cortef label details IV and IM use, rapid hydrocortisone activity, and major neurologic, endocrine, and infection…

DailyMed label for Mucinex Nightshift Cold and Flu details ingredients, dosing limits, liver warnings, sedation risks, and age…

Engineered peptides modeled on alpha-synuclein blocked VDAC in lipid membranes, offering a proof-of-principle for mitochondrial channel pharmacology.

A multiplex LC-MS/MS assay measured eight antibiotics in ICU serum samples and linked renal function, dose, sex, and…

A 2024 review maps the preclinical and clinical progress of mRNA drugs, from vaccines to non-immunogenic therapies, and…

HHS temporarily allows compounding of six experimental peptides, including BPC-157 and TB-500, despite FDA scientist concerns over evidence…

A 2025 tutorial details how University of Florida Health implemented Epic’s Genomics module to support pharmacogenomics clinical decision…

Pharmacology

Trials, guidelines and clinical evidence across Pharmacology.

In Brief The 5-minute rounds