Genomics

Clinical evidence, research, and medical intelligence in Genomics.

GeneSPOT maps spatial gene dynamics across tissue and time

GeneSPOT is a gene-centric spatial omics framework that tracks how molecular relationships shift across tissues, conditions, and development.

Sedimentary ancient DNA from a Norwegian Iron Age courtyard recovered plant and animal traces missed by archaeology and…

Across 27 UK Biobank traits, genomic foundation models failed to outperform baselineLD for common variant discovery and added…

Whole-genome alignment across Brassicaceae uncovers 22,377 de novo genes, branch-specific birth and death rates, and genomic factors shaping…

PigGPA links domain knowledge with hashed execution checks to improve reproducibility in porcine genomic breeding and functional analysis…

StarTrak integrates mutations, images, and spatial data to reconstruct cell lineages and migration in tissue sections at single-pixel…

A policy analysis maps genetic data risks, AI-driven misuse, and regulatory gaps, then proposes protections for privacy and…

A chromosome-level Falcataria falcata genome assembly links ancient polyploidy, duplicate-gene retention, and lineage-specific evolution in Fabaceae.

A 20th anniversary commentary examines genomics submissions to PLOS Computational Biology since 2017 and reflects on how the…

Progressive fine-tuning adapted the Evo genome foundation model for 7 DNA classification tasks across 24 datasets, improving functional…

Genomics

Clinical evidence, research, and medical intelligence in Genomics.

In Brief The 5-minute rounds