Transplantation

Clinical evidence, research, and medical intelligence in Transplantation.

Gene-Edited Pig Liver Xenotransplantation Faces Major Translation Barriers

A Frontiers in Immunology review details progress in gene-edited pig liver xenotransplantation and the immune, coagulation, and viral barriers ahead.

By Dr. A. Nikhil Krishnan, MBBS · 7 days ago · 6 min read

Transplantation·Front Immunol

Eculizumab Does Not Prove Added AMR Prevention in High-Risk Kidney Transplantation

Systematic review finds no randomized proof that peri-transplant eculizumab reduces antibody-mediated rejection in high-risk kidney transplant recipients.

Oct 28, 2026

Transplantation·Gut

MXene Gavage Strategy Aims to Reduce Nanotoxicity in Transplant Models

An opinion piece proposes gavage delivery of bile acid-modified MXenes to preserve immunosuppression while reducing bloodstream exposure and…

Oct 25, 2026

Transplantation·Nature

cDCD Lung Transplant Model Links Necroptosis to Graft Injury

A rat cDCD lung transplant model tied prolonged warm ischemia to graft injury and found RIPK1 inhibition improved…

Oct 24, 2026

Transplantation·Lancet Onc

Transplant Need Estimation Is Central to Equitable Service Planning

The Lancet Oncology authors’ reply argues that precise estimates of unmet transplant need are essential for fair, effective…

Oct 17, 2026

Transplantation

Clinical evidence, research, and medical intelligence in Transplantation.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.