Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Pope resumes Latin America tour weeks after lung cancer surgery

Pope Leo XIV resumed a 12-day Latin America tour three weeks after lung cancer surgery, citing recovery and access to timely care.

By Dr. Revathy Mohan V.R., MBBS · 5 days ago · 5 min read

Oncology·BBC Dental

Breast Cancer Charity Carries Family Legacy After Mother’s Death

Amy Leslie keeps letters from her mother, who died of breast cancer, while carrying on a family charity…

5 days ago

Oncology·Nature

Baseline Heterogeneity Masks Xenograft Treatment Effects, Study Finds

Baseline tumour volume heterogeneity can hide real responder signals in xenograft studies, limiting pooled analysis in preclinical oncology.

5 days ago

Oncology·bioRxiv

Methionine Cycle Target Emerges in Mesenchymal Pancreatic Cancer Cells

A preprint links SAHH-driven methionine cycling to mesenchymal pancreatic cancer, metastasis, and poor survival in PDA.

5 days ago

Oncology·bioRxiv

Shikonin reduces bone cancer pain in rats via spinal IGF2-p38 signaling

In a rat model of bone cancer pain, intrathecal shikonin reduced hypersensitivity, gait deficits, and anxiety-like behavior through…

5 days ago

Oncology·Med News Today

Pancreatic Cancer Vaccine Elicits Strong Immune Response in Phase 2 Trial

Camupepimut generated robust KRAS-directed immunity in pancreatic cancer, but the phase 2 trial did not reach significant disease-free…

5 days ago

Oncology·JCO

211At-CD45 Radioimmunotherapy Shows Early Activity in HCT Conditioning

First-in-human 211At-CD45 radioimmunotherapy was feasible before allogeneic HCT, with liver toxicity setting the dose limit and early antitumor…

6 days ago

Oncology·JCO

Financial navigation improves financial toxicity in multisite oncology trial

A multisite oncology financial navigation program improved financial toxicity scores across rural and nonrural practices in a pragmatic…

6 days ago

Oncology·JCO

Hypofractionated PMRT Matches Conventional IMNI Control in Phase III Trial

A phase III trial found 16-fraction postmastectomy radiotherapy with internal mammary node irradiation was noninferior for control and…

6 days ago

Oncology·JCO

Circulating eosinophils predict recurrence in HR-positive HER2-negative breast cancer

Circulating eosinophils tracked with immune activation, lower recurrence risk, and CDK4/6 inhibitor benefit in HR-positive HER2-negative breast cancer.

6 days ago

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.