Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Mutant KRAS Vaccine Shows Early Immune Activity in Pancreatic Cancer

A first-in-human mutant KRAS vaccine triggered durable T-cell responses in high-risk pancreatic cohorts, with G12D showing the weakest immunity.

By Dr. Revathy Mohan V.R., MBBS · 4 days ago · 5 min read

Oncology·Br J Cancer

Dietary diversity linked to lower breast cancer odds in case-control study

A case-control study found higher dietary diversity was linked to lower breast cancer odds, while the Alternative Healthy…

4 days ago

Oncology·Lancet Onc

Pumitamig Plus Nab-Paclitaxel Shows High Response in Triple-Negative Breast Cancer

A phase 1b/2 trial found pumitamig plus nab-paclitaxel produced a 73.8% response rate in advanced triple-negative breast cancer…

5 days ago

Oncology·Nature

DExT ex vivo drug testing detects mTOR response in kidney cancer tissue

Direct ex vivo drug testing measured acute mTOR pathway suppression in clear cell renal cell carcinoma tissue, supporting…

5 days ago

Oncology·JCO

ER Positivity and CDK4/6 Response in Breast Cancer

Scraped abstract title raises a biomarker question in breast cancer, but no methods, results, or endpoints were available…

5 days ago

Oncology·Gut

Pancreatic cancer study finds sex-based survival difference after nCRT

Women with resected pancreatic cancer had better survival after neoadjuvant chemoradiotherapy, linked to stronger antitumour immunity and fewer…

5 days ago

Oncology·Gut

Diet-Microbiota Axis Emerges as CRC Target in Review

A review links diet, microbiota, inflammation and colorectal cancer, outlining microbial biomarkers and microbiota-targeted strategies for future prevention.

5 days ago

Oncology·Front Immunol

SCART plus HFRT rapidly debulked bulky metastatic NSCLC in case report

A case report describes rapid shrinkage and symptom relief in bulky metastatic non-small cell lung cancer after SCART,…

5 days ago

Oncology·Front Immunol

Glofitamab Clears Early CNS Relapse in Pediatric Burkitt Lymphoma Case

A pediatric Burkitt lymphoma case report describes rapid CNS clearance with glofitamab, intrathecal rituximab, and ICE as a…

5 days ago

Oncology·Front Immunol

MCL-1 Cancer Targeting Shifts Toward Degradation and Combination Therapy

A Frontiers review traces how MCL-1 cancer therapy is moving from direct inhibition to degradation strategies amid cardiac…

5 days ago

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.