Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Fasting-Mimicking Diet Rewires Fibroblasts in Breast Cancer Microenvironment

A breast cancer study reports that fasting-mimicking diets can reprogram cancer-associated fibroblasts and weaken an immunosuppressive tumor microenvironment.

By Dr. Revathy Mohan V.R., MBBS · 6 days ago · 5 min read

Oncology·Sci Transl Med

Single-Cell Atlas Maps Pan-Cancer Liver Metastasis Programs

A 100-sample single-cell atlas maps 460,000 cells in liver metastases, linking immune escape, stromal remodeling, and tumor evolution…

6 days ago

Oncology·Sci Transl Med

Science issues erratum for chemo-immune nanoplatform cancer study

Science published an erratum for a chemo-immune nanoplatform cancer study on enzyme-sensitive dual-drug delivery and cascade targeting.

6 days ago

Oncology·Sci Transl Med

Science Erratum Issued for CD38 and Tumor Regulatory T Cell Study

Science published an erratum for a tumor immunology study on CD38-mediated metabolic reprogramming in regulatory T cells, with…

6 days ago

Oncology·Sci Transl Med

Theranostic fluorescent probes gain traction in tumor-targeted drug delivery

A Chemical Reviews article examines theranostic fluorescent probes for tumor-responsive drug delivery and other emerging applications in infection…

6 days ago

Oncology·PLOS Med

Single-cell study maps immune differences across breast cancer subtypes

Single-cell RNA sequencing reveals subtype-specific immune cell states, transcription factors, and signaling pathways across breast cancer.

6 days ago

Oncology·PLOS Med

Exposome Framework May Explain Alcohol-Related Cancer Risk

A PLOS Biology perspective argues the exposome may explain why alcohol drives cancer differently across people, tissues, and…

6 days ago

Oncology·JAMA IM

Gender-Diverse Breast Cancer Cohort Shows Younger Age and Favorable 5-Year Survival

In 112 gender-diverse patients with breast cancer, tumors were often self-detected, early stage, and hormone receptor positive, with…

6 days ago

Oncology·Front Immunol

Vulvar Squamous Cell Carcinoma TME Study Links pDCs and Macrophages to Outcomes

In HPV-independent vulvar squamous cell carcinoma, CD123+ plasmacytoid dendritic cells predicted better survival, while CD163+ macrophages tracked with…

6 days ago

Oncology·Front Immunol

Immunoproteasome-Reprogrammed MSCs Expose an Invisible Cancer Epitope Fraction

Pilot immunopeptidomics analysis finds a prediction-invisible peptide fraction in immunoproteasome-reprogrammed MSCs, challenging binding-only epitope models.

6 days ago

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.