Quizartinib Resistance in FLT3 Mutants Tied to Two Structural Escape Routes
Molecular simulations and cell assays map how FLT3 D835Y and F691L weaken quizartinib binding in AML by destabilizing the inactive kinase state.
By Dr. Revathy Mohan V.R., MBBS
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2 days ago
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5 min read