Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Deep learning model tracks bladder cancer outcomes after BCG therapy

A BERT-based EHR model measured recurrence and progression in NMIBC patients receiving BCG, with strong performance after limited human review.

By Dr. Revathy Mohan V.R., MBBS · 3 days ago · 5 min read

Oncology·JCO

CT Follow-up During Adjuvant Nivolumab in Esophageal Cancer

Multicenter real-world data suggest routine CT during adjuvant nivolumab detects most recurrences in resected esophageal cancer, while baseline…

3 days ago

Oncology·JCO

Renal Cell Carcinoma Study Examines Social Needs Documentation Gaps

JCO analysis examines documented health-related social needs in renal cell carcinoma and how prevalence differs across sociodemographic groups.

3 days ago

Oncology·JCO

Oral Cavity Squamous Cell Carcinoma Mutations and Prognosis in Real-World Data

Clinico-genomic analysis in oral cavity squamous cell carcinoma examines prognostic effects of tumor suppressor and DNA repair gene…

3 days ago

Oncology·JCO

Nimotuzumab, S-1, and Radiotherapy Studied in Older Esophageal Cancer Patients

Phase 2 study examines nimotuzumab with S-1 and concurrent radiotherapy for elderly patients with esophageal squamous cell carcinoma.

3 days ago

Oncology·JCO

GLP-1 Receptor Agonists and HCC Outcomes With Atezolizumab-Bevacizumab

An ASCO abstract examines whether GLP-1 receptor agonists affect outcomes in hepatocellular carcinoma patients receiving atezolizumab plus bevacizumab.

3 days ago

Oncology·JCO

HER3-DXd Phase II Trial Expands Into Multiple Advanced Solid Tumors

HERTHENA-PanTumor01 is testing patritumab deruxtecan in relapsed advanced solid tumors, including melanoma, gastric, ovarian, and prostate cancer.

3 days ago

Oncology·Blood

Adult BCR::ABL1-Negative B-ALL Genetic Profiling by Optical Genome Mapping

The abstract title points to a genetic profiling study in adult BCR::ABL1-negative B-ALL using optical genome mapping and…

3 days ago

Oncology·Gut

Single-cell profiling maps gastric cardia adenocarcinoma stemness and targets

Single-cell profiling of gastric cardia adenocarcinoma identifies drivers of cancer stemness and points to therapeutic targets in a…

3 days ago

Oncology·Gut

Norepinephrine drives aggressive intrahepatic cholangiocarcinoma via ADRB2

Sympathetic signaling fueled intrahepatic cholangiocarcinoma with perineural invasion through ADRB2, while beta-blockade showed preclinical suppression.

3 days ago

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.