Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

Type 2 Diabetes in Sjögren’s Disease Linked to Distinct Serology, Metabolic Burden

In Sjögren’s disease, type 2 diabetes tracked with higher metabolic burden and lower anti-SSB/La and C3 positivity in a multicenter real-world study.

By Dr. A. Nikhil Krishnan, MBBS · 3 days ago · 5 min read

Rheumatology·Cancer Cell

Smart Polymer Nanoparticles Offer New Rheumatoid Arthritis Therapy Strategy

Smart polymer nanoparticles may rebalance macrophages, suppress fibroblast invasion, and reshape the rheumatoid arthritis joint microenvironment.

3 days ago

Rheumatology·ARD

Primary Sjögren’s Syndrome Prevalence in Europe Raises Orphan Disease Debate

A critical appraisal of European prevalence studies examines whether primary Sjögren’s syndrome fits orphan disease thresholds and why…

3 days ago

Rheumatology·ARD

Peri-articular Oxygen Saturation in Arthritis Draws Focus at ARD

An Annals of the Rheumatic Diseases abstract examines peri-articular oxygen saturation in patients with arthritis, probing tissue anoxia…

3 days ago

Rheumatology·ARD

Remibrutinib Improves ESSDAI in Sjögren’s Syndrome Phase 2 Trial

Phase 2 data show remibrutinib lowered ESSDAI in Sjögren’s syndrome over 24 weeks, with no ESSPRI benefit and…

3 days ago

Rheumatology·MedCity

Nkarta autoimmune cell therapy shows early efficacy in myositis and systemic sclerosis

Nkarta’s NKX019 showed early safety and response signals in myositis and systemic sclerosis, setting up FDA talks on…

3 days ago

Rheumatology·ARD

Interferon-α signature predicts poor response in early rheumatoid arthritis

In early rheumatoid arthritis, a baseline interferon-α gene signature predicted worse 6-month outcomes and epigenetic changes in B…

4 days ago

Rheumatology·ARD

EULAR sets core competence standards for rheumatology health professionals

EULAR recommendations define generic core competences for rheumatology nurses, physical therapists and occupational therapists to guide postgraduate education.

4 days ago

Rheumatology·ARD

Imaging for Axial Spondyloarthritis: CT Outperforms X-ray in Diagnosis

CT and MRI outperformed radiography for diagnosing axial spondyloarthritis, with CT delivering the best accuracy and inter-rater reliability.

4 days ago

Rheumatology·ARD

Gout research trends from 2012 to 2021 map global output and future hotspots

A bibliometric analysis of 5,535 gout papers maps global productivity, collaboration, and emerging mechanistic priorities from 2012 to…

4 days ago

Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.