Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Clonucopya links tumor clonal architecture to drug prioritization

Clonucopya connects subclonal inference with drug ranking, aiming to translate tumor heterogeneity into clone-level therapeutic options.

NICE has opened consultation on draft guidance for nirogacestat in desmoid tumours, with comments due by 1 June…

Daraxonrasib’s FDA approval in metastatic pancreatic cancer expands access, but the label’s second clause has drawn criticism for…

Global cancer burden is set to rise as incidence and mortality vary by region, forcing health systems to…

Nature Reviews argues next-generation oncolytic viruses act as in situ cancer vaccines, broadening T cells and reshaping immunotherapy…

A Nature review examines GPC3-targeted CAR T cells in hepatocellular carcinoma, with early activity tempered by antigen loss…

A Nature Reviews Clinical Oncology review explains how the extracellular matrix may improve cancer biomarkers, imaging, drug delivery,…

Integrated single-cell, TCGA, and mouse data link SP1 to inflammatory remodeling, immune features, and malignant progression in ESCC.

Pope Leo XIV made his first public appearance after lung cancer surgery, recovering in hospital after removal of…

Astellas traces CLDN18.2 from tumor biology to biomarker-driven care, with gastric cancer testing, sequencing questions, and new solid…

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds