Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Gold nanoparticles made inside bacteria boost photothermal cancer therapy

A bioRxiv preprint describes bacterial gold nanoparticle synthesis using EcN and near-infrared heating that reached 75.4 C in vitro.

By Dr. Revathy Mohan V.R., MBBS · 3 days ago · 5 min read

Oncology·bioRxiv

Oncolytic vaccinia engineered to support off-the-shelf NK cell therapy

Researchers engineered oncolytic vaccinia to create a synthetic support niche for frozen NK cells, boosting antitumor activity while…

3 days ago

Oncology·Br J Cancer

SLC25A1 links citrate metabolism to SASP inflammation in senescent cells

Mitochondrial citrate export fuels histone acetylation at SASP genes, while SLC25A1 inhibition suppresses inflammation without reversing cell-cycle arrest.

3 days ago

Oncology·Br J Cancer

TrkA-CD44v3 Targeting Restores Entrectinib Activity in TNBC Brain Metastasis

Preclinical data show CD44v3 blockade restored Entrectinib response in TrkA-overexpressing triple-negative breast cancer brain metastasis models.

3 days ago

Oncology·Br J Cancer

Cancer drug resistance demands a temporal model of adaptive buffering

A Nature review reframes cancer drug resistance as a time-dependent process driven by adaptive buffering, cell plasticity and…

3 days ago

Oncology·Cancer Cell

Nanomedicine Targets Tumor Metabolism to Strengthen Cancer Immunotherapy

A review examines how nanomedicine can modulate tumor metabolism to improve immunotherapy while avoiding damage to effector T…

3 days ago

Oncology·Cancer Cell

Adipose eosinophil heterogeneity links sex, RELMα, and obesity inflammation

Single-cell profiling identified sex- and RELMα-linked adipose eosinophil states in obesity, with altered macrophage communication networks and regulatory…

3 days ago

Oncology·Cancer Cell