Neurology

From stroke to neurodegeneration — the science and its clinical impact.

TCGX backs TriGemX SPAC to fund migraine drug elismetrep

TCGX will take TriGemX public via SPAC, funding phase 3 development of elismetrep, a TRPM8 blocker in acute migraine.

Recent guideline updates and landmark trials are moving recurrent ischemic stroke prevention from blanket therapy to mechanism-based, individualized…

New research shows glioblastoma and astrocytes exchange mitochondria through tunnelling nanotubes, a pathway that may help tumour cells…

Longitudinal sleep data in 18 presymptomatic gene carriers show progressive ALS-related abnormalities before motor symptoms emerge.

Proteomic shifts during menopause tracked with sex hormones and poorer cognitive outcomes, linking midlife hormonal change to brain…

Longitudinal blood profiling linked pre-relapse multiple sclerosis to EBV-responsive B cells, atypical B-cell expansion and shared genetic risk…

Nature Reviews Neurology examines complement biology, approved neurologic drugs, and phase I-III trials reshaping autoimmune and degenerative CNS…

A theoretical model links sleep-dependent memory consolidation to free cortical units and proposes a possible epigenetic pathway in…

Higher weekly physical activity was tied to slower cognitive and motor decline in Parkinson’s disease over years of…

A preprint describes RePurpose, an LLM-assisted drug repurposing tool that traced clemastine evidence in multiple sclerosis using linked…

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds