Neurology

From stroke to neurodegeneration — the science and its clinical impact.

Blood biomarker panel distinguishes Alzheimer disease from controls in validation study

A single-center cross-validation study found a blood biomarker panel separated Alzheimer disease from healthy controls with near-perfect internal accuracy.

By Dr. A. Manasa, MBBS · 2 days ago · 5 min read

Neurology·NIH

Krabbe Disease Surveillance Prioritizes Feeding, Neurologic, and Respiratory Monitoring

GeneReviews surveillance for symptomatic Krabbe disease calls for ongoing monitoring of feeding, neurologic, developmental, respiratory, and family support…

2 days ago

Neurology·medRxiv

Acute Intermittent Hypoxia Improves Walking and Strength in Multiple Sclerosis

A five-day acute intermittent hypoxia protocol was safe in MS and improved ankle plantarflexion strength and walking endurance…

2 days ago

Neurology·medRxiv

CDC123 variants linked to neurodevelopmental delay impair protein synthesis

Rare CDC123 missense variants in four families disrupted eIF2 assembly, reduced protein synthesis, and were linked to pediatric…

2 days ago

Neurology·medRxiv

WALRUS deep learning improves water and lipid removal in 1H-MRSI

WALRUS uses calibrated deep learning to improve water and lipid removal in 1H-MRSI, simplifying inference and strengthening metabolite…

2 days ago

Neurology·bioRxiv

ALS spatial proteomics maps early astrocytic remodeling in mouse spinal cord

Repurposed sequencers and spatial proteomics mapped early astrocytic remodeling around motor neurons in the SOD1-G93A ALS mouse model.

2 days ago

Neurology·BBC Dental

Bedrolite supply crisis threatens epilepsy control for UK patients

Families fear seizure relapse as bankruptcy threatens Bedrolite supplies for severe epilepsy patients in the UK, despite short-term…

2 days ago

Neurology·Br J Cancer

Dementia resistance genes reveal new Alzheimer’s protection clues

Rare protective gene variants may explain why some people avoid dementia despite high Alzheimer’s risk, pointing to new…

2 days ago

Neurology·bioRxiv

C9orf72 ALS/FTD fly study links lysosome failure to DPR secretion

Drosophila data tie presymptomatic lysosomal dysfunction to toxic DPR secretion in C9orf72 ALS/FTD and point to valproic acid’s…

2 days ago

Neurology·Med News Today

Lifetime Estrogen Exposure Linked to Healthier Brain Vessels in Older Women

An observational study found longer estrogen exposure, including hormone therapy, was associated with better white matter and less…

2 days ago

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.