Neurology

From stroke to neurodegeneration — the science and its clinical impact.

Activated Clotting Time Targets Lowered for Heparin in Neurointerventional Radiology

An academic medical center found i-STAT ACT readings more reproducible than Hemochron and lowered the heparin target range in neurointerventional radiology.

By Dr. A. Manasa, MBBS · 5 days ago · 4 min read

Neurology·AHA

Spironolactone Lowers Blood Pressure After Stroke in REDUCE Trial

Spironolactone lowered home systolic blood pressure after stroke and helped more patients reach goal, with similar serious side…

5 days ago

Neurology·ScienceDaily

Coffee intake linked to lower dementia risk in 43-year study

Regular caffeinated coffee intake, especially 2 to 3 cups daily, was associated with lower dementia risk and better…

5 days ago

Neurology·ScienceDaily

Psilocybin Rewires Brain Circuits Without Hallucinations in Mice

UC Santa Cruz scientists mapped how psilocybin reshapes synapses in mice and separated circuit rewiring from a psychedelic…

5 days ago

Neurology·ScienceDaily

Broccoli compound sulforaphane shows promise for Friedreich ataxia

Sulforaphane from broccoli increased frataxin and protected nerve cells in preclinical Friedreich ataxia research, setting up clinical trial…

5 days ago

Neurology·Br J Cancer

Machine learning classifies multiple sclerosis subtypes from blood transcripts

Three ensemble models classified multiple sclerosis and its subtypes from blood transcriptomes, suggesting a feasible route to less…

5 days ago

Neurology·bioRxiv

Dual kinase inhibition slows Parkinson’s pathology in AAV-haSyn rat model

URMC-099 reduced nigral-striatal pathology and motor asymmetry in a rat Parkinson’s model by inhibiting MLK3 and LRRK2 together.

5 days ago

Neurology·PLOS Med

CVT-Related Intracranial Hypertension Linked to Persistent Headache and Visual Field Loss

In a tertiary cohort, CVT-related intracranial hypertension left most patients with preserved acuity but frequent headache, field loss,…

6 days ago

Neurology·PLOS Med

RNA granule imaging in live mouse brain gets a sensitivity boost

An amplified MS2 system improved detection of RNA granules in fresh mouse brain slices and revealed cell-type-specific mRNA…

6 days ago

Neurology·Nat Rev Onc

Alzheimer’s disease prevention may need a vascular rethinking

An Alzheimer’s disease commentary argues hypertension and vasoconstriction deserve more attention than amyloid alone, with vasodilators as a…

6 days ago

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.