Immunology

Clinical evidence, research, and medical intelligence in Immunology.

ME/CFS Study Links Aging Genes SGK1 and HMGCR to Senescence Signatures

A PLOS One analysis ties ME/CFS to aging-related gene signals, with SGK1 and HMGCR emerging as candidate markers of senescence pathways.

A mechanistic discussion of how mRNA splicing connects surface immunity with NLR activation, and why that matters for…

Adult PCV13 responses showed rapid memory B cell expansion but delayed germinal center activity with limited polysaccharide specificities.

In type 1 diabetes, intradermal GAD-alum challenge and single-cell sequencing identified rare autoreactive T cells in skin and…

Source text contains only the title and author list, without the article body needed for an accurate clinical…

CAR T cell therapy is moving beyond cancer, with early anti-CD19 results in lupus fueling broader autoimmune research…

Emails show a leading immunology association split over an $8.4 billion California ballot measure aimed at funding the…

In mouse models, excess IL-18 promoted HLH/MAS by impairing NK cells and driving nonspecific T-cell hyperactivation during viral…

Obesity reduces circulating Vδ2 T cell frequency and function by disrupting amino acid sensing and mTORC1 signaling, with…

Qβ-VLP vaccines against ASC lowered IL-1β, neutrophil activation, and tau pathology in mouse models while preserving infection responses.

Immunology

Clinical evidence, research, and medical intelligence in Immunology.

In Brief The 5-minute rounds