Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

Single-cell profiling links kidney CD163+ dendritic cells to lupus nephritis

Single-cell profiling points to CD163+ dendritic cell involvement in human lupus nephritis, adding a new layer to renal immune pathology.

By Dr. A. Nikhil Krishnan, MBBS · Oct 24, 2026 · 5 min read

Rheumatology·ARD

MRI Definition of Active Sacroiliitis Updated for Axial Spondyloarthritis

ASAS MRI working group updates the definition of a positive MRI for axial spondyloarthritis, keeping bone marrow oedema…

Oct 24, 2026

Rheumatology·ARD

ACR/EULAR remission definition for rheumatoid arthritis clinical trials

ACR and EULAR propose two uniform remission definitions for rheumatoid arthritis trials, including a Boolean measure and the…

Oct 24, 2026

Rheumatology·ARD

Rheumatoid Arthritis Help-Seeking Delays Tied to Symptom Misinterpretation

Qualitative synthesis shows how symptom normalization, low RA awareness, and care-access barriers delay help-seeking at rheumatoid arthritis onset.

Oct 24, 2026

Rheumatology·ARD

COVID-19 Booster Trial in Rituximab-Treated Patients Finds Similar Response

In rituximab-treated patients who failed to seroconvert after mRNA vaccination, a third dose produced similar antibody responses with…

Oct 24, 2026

Rheumatology·ARD

SLE Risk Probability Index aims to sharpen lupus diagnosis

A machine learning-based SLE Risk Probability Index is designed to help clinicians distinguish lupus from look-alike conditions more…

Oct 24, 2026

Rheumatology·ARD

COVID-19 severity risk factors in psoriasis, PsA and axSpA identified

Registry data from 5,045 patients links age, sex, comorbidity burden, disease activity and glucocorticoids to worse COVID-19 outcomes.

Oct 24, 2026

Rheumatology·ARD

Rheumatoid Arthritis: Opioids Not Safer Than NSAIDs for Cardiovascular Risk

In rheumatoid arthritis, opioid initiation carried similar MACE risk to NSAIDs but higher all-cause mortality and likely more…

Oct 24, 2026

Rheumatology·Br J Cancer

15-PGDH inhibition in osteoarthritis raises cartilage repair hopes and safety questions

A Bone Research review examines 15-PGDH inhibition in osteoarthritis, linking PGE2 skeletal interoception, cartilage repair and compartment-specific risk.

Oct 24, 2026

Rheumatology·DailyMed

Tofacitinib label warns of infection, clot and cardiovascular risks

DailyMed label for tofacitinib extended-release tablets details boxed safety risks, monitoring needs, and approved inflammatory disease uses.

Oct 24, 2026

Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.