Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

PRDM1-ATG5 Autophagy Signal Linked to SLE in Chinese Cohort

A Chinese genetic study links the PRDM1-ATG5 region and autophagy genes to systemic lupus erythematosus, implicating ATG5, ATG7 and IRGM.

CAR T therapy for rheumatic disease has produced deep B-cell depletion, remission, and immune reset signals, with safety…

A study in rheumatoid arthritis examines whether disease activity, cytokines and chemokines help explain incident diabetes risk.

Single-cell RNA sequencing of PMR blood cells found fewer T cells, more megakaryocyte/platelet signals, and activated interferon-linked monocytes.

A 54-year-old woman with systemic lupus erythematosus developed axial spondyloarthritis, illustrating MRI-based diagnosis and sulfasalazine response.

Preclinical work links LIF to arthritis pain, showing cytokine-driven neuronal sensitization, neurite outgrowth, and pain-like behavior in models.

An international rheumatoid arthritis collaboration evaluates adverse-event discontinuation patterns for JAK inhibitors and biologic DMARDs.

A bibliometric atlas of 1,118 papers maps Sjögren’s syndrome biomarker research, led by China, the US, and emerging…

Synovial cellular and molecular signatures identified early rheumatoid arthritis patients more likely to respond to csDMARDs and progress…

EULAR task force recommendations on early arthritis focus on rapid assessment, risk stratification, and timely treatment to limit…

Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

In Brief The 5-minute rounds