Pulmonology

Trials, guidelines and clinical evidence across Pulmonology.

Upper Respiratory Tract Infection Guidance Targets Adult Symptom Control

Asia-Pacific experts issued a multidisciplinary framework for adult upper respiratory tract infection care, emphasizing concurrent symptom relief and safer self-management.

By Dr. A. Nikhil Krishnan, MBBS · Nov 6, 2026 · 5 min read

Pulmonology·Nature

Estradiol Reduced Lung Ischemia-Reperfusion Injury in Male Rats

In rats, 17β-estradiol lessened lung ischemia-reperfusion injury in males and restored PI3K/AKT/GSK-3β signaling after reperfusion.

Nov 5, 2026

Pulmonology·Nature

Chatbot Answers on Pulmonary Aspergillosis Varied Sharply Across Platforms

Four AI chatbots produced uneven, often unreadable pulmonary aspergillosis answers, with Copilot and Perplexity scoring higher on quality…

Nov 5, 2026

Pulmonology·JCI

Pulmonary Hypertension Linked to Cerebellar-Frontal Brain Changes

MRI and biomarker data link pulmonary hypertension to cerebellar-frontal brain injury, executive dysfunction, and inflammatory pathways involving NCOA7.

Nov 5, 2026

Pulmonology·Nature

COPD Proteomics Panel Distinguishes Disease From Asthma and Smoking

Shotgun proteomics identified five serum proteins that separated COPD from asthma, smokers, and controls, with cross-validated models exceeding…

Nov 4, 2026

Pulmonology·Nature

HFNC Failure Model in Older Adults With COVID-19 Fails Cross-Site Validation

A random-forest model predicted HFNC failure in older adults with COVID-19 in one cohort, but cross-site performance was…

Nov 4, 2026

Pulmonology·PLOS ONE

5-HMF Exposure May Worsen Pulmonary Fibrosis in PLOS One Study

A PLOS One study links dietary 5-HMF to worse bleomycin-induced pulmonary fibrosis in mice and identifies fibrosis-related molecular…

Nov 4, 2026

Pulmonology·JAMA IM

COPD Years of Life Lost Offer Prognostic Signal, Not Recovered Life-Years

JAMA Internal Medicine authors clarify that COPD-related years of life lost reflect prognosis from baseline airflow obstruction, not…

Nov 4, 2026

Pulmonology·Lan GH

New Zealand asthma guidelines drove ICS-formoterol uptake but left SABA-only use entrenched

A national patient-level study in New Zealand found guideline-recommended ICS-formoterol use rose after 2020, while many SABA-only patients…

Nov 3, 2026

Pulmonology·JCI

PAH-linked cerebellar impairment connects lung vascular disease to brain injury

PAH is tied to cerebellar white matter loss, frontal thinning, and cognitive deficits, with NCOA7-linked inflammatory pathways implicated…

Nov 3, 2026

Pulmonology

Trials, guidelines and clinical evidence across Pulmonology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.