Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

CAR-T toxicity prediction tools gain ground, but prospective validation remains absent

A 2026 Frontiers mini review maps validated CAR-T toxicity scores, led by CAR-HEMATOTOX, and the gap in prospective risk-guided trials.

JAMA Network Open issued an affiliation correction for an immunotherapy trial article, adding UCSF and Weill Cancer Hub…

Scoping review finds perioperative immune checkpoint inhibitor therapy is feasible, but requires careful screening for toxicities that can…

A review of ferroptosis in breast cancer examines iron metabolism, tumor heterogeneity, and biomarker strategies that may shape…

An expert commentary examines how trial design and commercial competition shape access inequities in multiple myeloma care.

ESMO Open abstract examines how adding a polygenic score may alter breast cancer risk stratification in carriers of…

CytoRipple uses cytoskeleton measurements in spatial multi-omic data to infer polarization vectors and uncover cell streams linked to…

JCI study shows that blocking glycosphingolipid synthesis suppresses osteoclast activation and improves murine multiple myeloma bone disease.

Retrospective mRCC cohort found 8.9% pneumonitis with ICIs, a strong association with prior chest radiation, and rare fatal…

Interviews in Rwanda found government support, community health workers, and an EHR helped scale women’s cancer screening, while…

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds