Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

GEP-NET spatial architecture mapped by single-cell multiomics

Single-cell and spatial profiling of 38 gastroenteropancreatic neuroendocrine tumors reveals conserved neuronal-like and secretory programs with niche-specific signaling.

By Dr. Revathy Mohan V.R., MBBS · Nov 4, 2026 · 5 min read

Oncology·JCI

Nuclear cGAS links cholesterol metabolism to tumor growth and therapy response

New JCI research maps nuclear cGAS on chromatin and connects it to cholesterol control, Akt-mTOR signaling, tumor growth,…

Nov 4, 2026

Oncology·JCI

PD-L1/TGF-beta blockade rapidly reshapes stroma in head and neck cancer

Neoadjuvant bintrafusp alfa rapidly altered stromal biology and increased CD8 T-cell infiltration in head and neck squamous cell…

Nov 4, 2026

Oncology·JCI

Neuroendocrine Tumor Cell States Offer New Classification Axis

Single-nucleus and spatial profiling identified two conserved neuroendocrine tumor cell states that may improve prognosis and treatment stratification.

Nov 4, 2026

Oncology·DailyMed

Dasatinib label update expands warnings for CML and Ph+ ALL

DailyMed’s updated dasatinib label outlines adult and pediatric uses, standard dosing, key drug interactions, and major safety risks.

Nov 4, 2026

Oncology·DailyMed

Methotrexate label update tightens safety rules across cancer and autoimmune use

Updated methotrexate labeling reinforces weekly dosing, pregnancy restrictions, infection monitoring, and boxed warnings across oncology and autoimmune care.

Nov 4, 2026

Oncology·WHO

Lung Cancer Awareness Month 2026 spotlights screening, tobacco control, and classification

IARC marks Lung Cancer Awareness Month 2026 with new estimates, screening evidence, tobacco control projections, and molecular classification…

Nov 4, 2026

Oncology·ScienceDaily

Cancer Cells May Be Used to Synthesize Their Own Killers

Japanese researchers turned tumor-associated carbon monoxide into a trigger for drug synthesis inside cancer cells in early lab…

Nov 4, 2026

Oncology·Nature

Diffuse Spectroscopy Tracks Early Cyclophosphamide Response in Breast Tumors

In a rat breast cancer model, diffuse reflectance and correlation spectroscopy detected oxygen and blood-flow changes before tumor…

Nov 4, 2026

Oncology·Nature

Melanoma Study Links Senescence and Ferroptosis to Tumor Cell Death

A preclinical melanoma study found that volasertib-induced senescence plus auranofin-driven ferroptosis amplified DNA damage and shrank tumors in…

Nov 4, 2026

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.