Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

COMFORT trial to test AI reading for kidney and prostate tumors

COMFORT will test whether AI-assisted reading improves kidney and prostate tumor assessment, clinician usability, fairness, and privacy risk.

AstraZeneca’s phase 1/2 Lumi-NHL study will test AZD4512 alone or with surovatamig in relapsed or refractory B-cell non-Hodgkin…

DKK1 expression in osteosarcoma tracked with worse survival, while circulating levels fell during treatment and localized to malignant…

Single-cell reanalysis of 391,444 glioma cells suggests drug response direction is coherent across tumor states, while magnitude varies.

An axillary lymph node deep learning model transferred across cervical, mediastinal, and abdominal stations, with site-specific margin tuning…

A habitat informed 3D deep learning approach is used to predict immunochemotherapy response in esophageal squamous cell carcinoma.

RepurNet introduces a network medicine framework for systematic drug repurposing and disease vulnerability discovery, with oncology as the…

FRα-directed BiTE-secreting T cells plus PD-1 blockade reshaped ovarian tumor immunity, with vaccine boosting further improving control in…

Global cancer cases in women aged 15-49 nearly doubled since 1990, while mortality fell overall, with major regional…

A review in cancer nanomedicine examines co-loaded delivery systems that may improve ratio control, immune activation, and tumor…

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds