Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Medulloblastoma Workshop Sets Priorities for High-Risk Pediatric Tumors

Experts prioritized SRC degradation, MYC-targeted strategies, and B7-H3 approaches to improve medulloblastoma outcomes while limiting toxicity.

Cancer mortality is far higher in deprived communities. This essay argues for tackling inequalities across prevention, diagnosis, treatment,…

A melanoma genomics commentary questions whether CBL meets driver-gene criteria, citing variant-level limitations and the need for functional…

An editorial warns that the CBL deletion signal in stage II melanoma weakens after adjustment, especially in the…

An ESMO Open abstract focuses on HPV circulating tumor DNA detection and tracking in Chinese cervical cancer during…

ESMO Open analysis examines 3P CD36 expression in the tumor microenvironment of high-grade serous ovarian cancer, a key…

Pope Leo XIV’s lung adenocarcinoma diagnosis brings attention to how this common lung cancer is found, staged, treated,…

A preprint models cancer cell metabolism with dynamic flux balance analysis, revealing media-dependent fluxes, lactate secretion, and shared…

A first-in-human Phase 1 study will test BA1203 in advanced solid tumors, focusing on safety, pharmacokinetics, and preliminary…

A Nature Reviews Clinical Oncology commentary frames new database evidence on vaping after smoking cessation and its uncertain…

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds