Neurology

From stroke to neurodegeneration — the science and its clinical impact.

Memory Variability Linked to Hippocampal White Matter in Older Latino Adults

Older Latino adults without dementia showed a link between memory variability and hippocampus-cingulum integrity, while mean memory tracked hippocampal volume.

By Dr. A. Manasa, MBBS · Oct 25, 2026 · 5 min read

Neurology·medRxiv

AI Overlay Improves Neurologic Autoantibody Assay Reading

A preprint tested an AI boundary overlay for neurologic autoantibody assays, improving reader agreement but raising concern for…

Oct 25, 2026

Neurology·PLOS ONE

SOD2 Reduction Did Not Alter Prion Pathology in Mice, PLOS Correction Notes

PLOS ONE issued a correction to a mouse prion study after a figure swap, reaffirming that reduced SOD2…

Oct 25, 2026

Neurology·Nat Rev Onc

Epilepsy LLM improves seizure semiology localization of epileptogenic zones

A domain-adapted epilepsy language model outperformed baseline models and rivaled epileptologists in localizing epileptogenic zones from seizure narratives.

Oct 25, 2026

Neurology·BMJ Open

Dexmedetomidine Trial Targets Delirium After DBS in Parkinson’s Disease

A Chinese randomized trial will test whether 48-hour dexmedetomidine infusion can prevent delirium after deep brain stimulation in…

Oct 25, 2026

Neurology·JAMA Open

Intracerebral Hemorrhage Arrives Later Than Acute Ischemic Stroke in ED Care Study

A large US cohort found ICH patients arrived with more severe deficits and different adjusted ED timing patterns…

Oct 25, 2026

Neurology·WHO

The Gambia adopts first national dementia plan in WHO African Region

The Gambia has adopted the WHO African Region’s first national dementia plan, aiming to improve diagnosis, care, caregiver…

Oct 25, 2026

Neurology·Br J Cancer

RNA ends link genetic risk to brain disease in 379 human brains

Mapping alternative polyadenylation across 379 human brains ties genetic risk loci to RNA end choice and downstream disease…

Oct 25, 2026

Neurology·Front Immunol

AQP4 Antibody Injury Reshapes CNS Immunity in NMOSD Model

A combined mouse model shows AQP4-IgG drives astrocyte loss, complement activation, BBB disruption, and a B cell-skewed inflammatory…

Oct 25, 2026

Neurology·ScienceDaily

Low-dose aspirin may cut dementia risk in a genetic subgroup

Monash University analysis links low-dose aspirin to lower dementia risk in older adults with a platelet-related genetic profile,…

Oct 25, 2026

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.