Neurology

From stroke to neurodegeneration — the science and its clinical impact.

MFSD7c deficiency links FLVCR2 mutations to microcephaly vasculopathy

Mouse and human data tie MFSD7c deficiency to defective CNS angiogenesis, hypoxia, and microcephaly-associated vasculopathy in Fowler syndrome.

By Dr. A. Manasa, MBBS · Oct 26, 2026 · 5 min read

Neurology·medRxiv

Remote Speech Assessment Feasible in 1,000 Neurology Patients

A Mayo Clinic preprint found remote self-administered speech testing was feasible in 1,000 neurology patients, with quality gaps…

Oct 26, 2026

Neurology·Nat Rev Onc

Peripheral immune proteomics identifies early multiple sclerosis signals

Proteomic profiling of untreated early multiple sclerosis found cell-specific immune alterations in monocytes, B cells, T cells, and…

Oct 26, 2026

Neurology·PLOS Med

Oxidative signaling thresholds may explain neuronal vulnerability in neurodegeneration

An essay argues that neuronal injury depends on redox thresholds, not ROS load alone, with implications for selective…

Oct 26, 2026

Neurology·Nat Rev Neuro

Multi-organ imaging genetics reframes brain disease as a whole-body problem

A Nature Reviews Neurology perspective maps how multi-organ imaging genetics links brain disease with heart, retina and other…

Oct 26, 2026

Neurology·Br J Cancer

Amygdala signals linked to cooperation in social dilemmas

Intracranial recordings in epilepsy-patient dyads mapped an amygdala-driven pathway for mutual cooperation during a real-time prisoner’s dilemma.

Oct 26, 2026

Neurology·Br J Cancer

Dopamine amplifies delayed subthalamic responses in Parkinson’s disease

In 15 Parkinson’s disease patients, dopamine selectively amplified long-latency subthalamic responses while leaving fast hyperdirect transmission intact.

Oct 26, 2026

Neurology·Br J Cancer

Plasma eMTBR-tau243 advances Alzheimer’s tau staging and prognosis

Plasma eMTBR-tau243 and p-tau205 track later tau pathology in Alzheimer’s disease and may improve biological staging and prognosis.

Oct 26, 2026

Neurology·Harvard Health

Dementia vs Depression: How to Tell the Difference in Older Adults

Older adults with cognitive decline may have depression rather than dementia. Learn the clinical clues that help separate…

Oct 26, 2026

Neurology·medRxiv

Memory Variability Linked to Hippocampal White Matter in Older Latino Adults

Older Latino adults without dementia showed a link between memory variability and hippocampus-cingulum integrity, while mean memory tracked…

Oct 25, 2026

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.