Immunology

Clinical evidence, research, and medical intelligence in Immunology.

TREM-2 corrigendum corrects supplemental figure in tuberculosis study

JCI published a corrigendum correcting an incorrect H&E image in Supplemental Figure 14G from its TREM-2 tuberculosis study.

By Dr. A. Nikhil Krishnan, MBBS · Nov 3, 2026 · 5 min read

Immunology·JCI

Treg Persistence and Necroptosis Inhibition in Autoimmune Disease

JCI study examines how blocking necroptosis may prolong regulatory T-cell survival and restrain autoimmune pathology through immune tolerance…

Nov 3, 2026

Immunology·Nat Rev Onc

Monoallelic inborn errors of immunity demand a systems-level view

A systems biology perspective reframes monoallelic inborn errors of immunity beyond variant-centric thinking, with implications for dominance, pleiotropy,…

Nov 2, 2026

Immunology·PubMed

Pyrin Inflammasome Links L-carnitine Uptake to Inflammation in Muscle Injury

Cell study shows OCTN2-mediated L-carnitine uptake activates the pyrin inflammasome in macrophages, linking muscle injury and red-meat exposure…

Nov 1, 2026

Immunology·JCI

LIG4 Mutation Mouse Model Links DNA Repair Failure to Intestinal Inflammation

A hypomorphic LIG4 mouse model developed severe Th1-skewed intestinal inflammation, revealing how defective DNA repair can reshape immune…

Nov 1, 2026

Immunology·MedCity

Bambusa IPO Funds Bispecific Antibodies for Atopic Dermatitis and Inflammation

Bambusa raised $169 million in its IPO to advance bispecific antibodies for atopic dermatitis, respiratory disease, and inflammatory…

Oct 31, 2026

Immunology·STAT

LNP-mRNA vaccines advance across infectious and cancer immunotherapy

LNP-mRNA vaccines are expanding beyond COVID-19, with engineered particles and mRNA chemistry driving stronger immune responses in preclinical…

Oct 30, 2026

Immunology·ScienceDaily

Sauna Session Briefly Raises White Blood Cell Counts in Finnish Study

A Finnish study found 30 minutes in a sauna temporarily raised circulating white blood cells and altered some…

Oct 29, 2026

Immunology·Br J Cancer

NLR proteins and inflammasome activation revealed by structural advances

A mini review details how distinct NLR proteins assemble inflammasomes, recruit caspase-1, and trigger pyroptotic inflammatory signaling.

Oct 28, 2026

Immunology·ScienceDaily

T cells sense tissue stiffness to build lasting immunity

McGill researchers found T cells can detect tissue stiffness, a mechanical cue that helps drive tissue-resident memory programs…

Oct 28, 2026

Immunology

Clinical evidence, research, and medical intelligence in Immunology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.