Immunology

Clinical evidence, research, and medical intelligence in Immunology.

CAR T Therapy Beyond Cancer Enters Autoimmunity, Fibrosis, and Infection

A 2026 review examines how CAR T platforms are being adapted for HIV, autoimmunity, fibrosis, transplantation, hemophilia, and senescence.

Granzyme K was elevated in systemic lupus erythematosus and tracked disease activity, inflammatory T-cell programs, and B-cell abnormalities…

New immunology research links extracellular galectin-3 to activated, antigen-experienced T cells through CD44 and PD-1, with apoptosis and…

CRISPR-Cas9 MPO knockout in human stem cells abolished chlorination and PMA-induced NETs while preserving key neutrophil effector functions.

CARTnet uses contact-aware attention and template-guided learning to improve B-cell epitope prediction across internal and external test sets.

Sanofi halted Nurix’s STAT6 degrader SAR448272 two months after phase 1 entry, ending a collaboration in type 2…

Yale is testing intradermal seasonal influenza vaccination with MicronJet to map skin and blood immune responses in healthy,…

Bat epithelial cells permitted rapid Toxoplasma gondii replication, while transcriptomic responses remained muted until late infection and damage…

A fixed 12-gene blood transcriptomic framework separated sepsis from non-infectious inflammation and linked key signals to granulocyte and…

A two-residue C-terminal AID truncation caused adult-onset hyper-IgM syndrome type 2 and blocked class-switch recombination in patient B…

Immunology

Clinical evidence, research, and medical intelligence in Immunology.

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