Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

Saudi Claims Data Reveal Diabetes Treatment Gaps in Private Insurance

National claims data from Saudi Arabia show substantial treatment switching, discontinuation and incomplete glycaemic monitoring among privately insured adults with type 2 diabetes.

By Dr. A. Nikhil Krishnan, MBBS · 4 days ago · 6 min read

Endocrinology·BMJ

ADA obesity drug guidance backs person-centered adult treatment

ADA obesity standards support pharmacologic treatment in adults alongside lifestyle care, with shared decision-making to improve weight and…

4 days ago

Endocrinology·BMJ

Semaglutide Ethics: Why Ozempic and Wegovy Raise Real Questions

A BMJ ethics analysis examines semaglutide’s popularity, weight-loss use, and the moral concerns that complicate prescribing Ozempic and…

4 days ago

Endocrinology·BMJ Open

Low Weight Loss Response to Incretin Analogs Tied to Baseline Risk Factors

A systematic review links weaker weight loss on GLP-1 and GIP analogs to higher baseline body weight, insulin…

4 days ago

Endocrinology·medRxiv

LLM Advice on Pediatric Hyperglycemia Raises Insulin-on-Board Safety Concerns

A medRxiv preprint found large language models can omit insulin-on-board warnings when advising pediatric hyperglycemia, raising safety concerns.

4 days ago

Endocrinology·bioRxiv

β-cell NCK1 loss in type 2 diabetes links stress response to insulin failure

A preprint reports reduced β-cell NCK1 in type 2 diabetes, with impaired unfolded protein response, weaker insulin secretion,…

4 days ago

Endocrinology·Cancer Cell

Acupuncture for Prediabetes Gains Evidence in Review of Clinical Trials

A review outlines how acupuncture and moxibustion may improve glucose control in prediabetes, while warning that trial quality…

4 days ago

Endocrinology·ScienceDaily

Miro1 Protein Linked to Insulin Resistance in Type 2 Diabetes

Researchers identified Miro1 as a muscle protein tied to insulin resistance in type 2 diabetes, and exercise lowered…

4 days ago

Endocrinology·BMJ

LEAN-PREP trial tests muscle preservation during semaglutide and tirzepatide therapy

LEAN-PREP will test whether resistance exercise and protein can preserve quadriceps muscle and function during semaglutide or tirzepatide…

4 days ago

Endocrinology·BMJ

Weight-loss drug race raises concerns over metabolic health and muscle loss

Drug makers are chasing 30% to 40% weight loss, but the push for bigger numbers risks overlooking muscle…

5 days ago

Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.