Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

Physical Activity and Diabetic Foot Risk in Swedish Type 2 Diabetes Cohort

Swedish registry data link physical activity with lower-extremity complications in type 2 diabetes, using landmarking and predictive modeling methods.

By Dr. A. Nikhil Krishnan, MBBS · 18 hrs ago · 5 min read

Endocrinology·NIH

LINK study tests food support and social care to improve diabetes control

The LINK trial will test produce access, diabetes education, and social needs navigation in food-insecure adults with type…

18 hrs ago

Endocrinology·ClinicalTrials

Incretin Therapy Study Tracks Muscle Loss in Obesity

A prospective Dutch cohort will track how semaglutide and tirzepatide affect fat-free mass, strength, and function during weight…

19 hrs ago

Endocrinology·medRxiv

Renin-Aldosterone Screening Predicts Long-term MACE Risk After PA Workup

Higher screening aldosterone-renin ratio and lower renin tracked with long-term MACE after primary aldosteronism evaluation, especially without adrenalectomy.

22 hrs ago

Endocrinology·Diabetes Care

ADA Guidance on Immunotherapy in New-Onset Type 1 Diabetes in Youth

ADA guidance addresses disease-modifying immunotherapy for children and adolescents with new-onset stage 3 type 1 diabetes.

1 day ago

Endocrinology·ClinicalTrials

KAI-4729 trial tests injection site and ethnicity effects on PK in obesity

Phase 1 trial will compare KAI-4729 pharmacokinetics across injection sites and ethnicity in adults with overweight or obesity.

2 days ago

Endocrinology·Becker H

THBS1 linked to adipose fibrosis and inflammation in metabolic disease

Single-cell profiling of human visceral fat links THBS1 to fibro-inflammation, impaired adipogenesis, and metabolic dysfunction in obesity and…

2 days ago

Endocrinology·medRxiv

Metformin Start Linked to Slightly Higher COVID Risk in T2D Cohort

In a large OpenSAFELY cohort of newly diagnosed type 2 diabetes, starting metformin was not protective against severe…

2 days ago

Endocrinology·bioRxiv

iPSC Transcriptomes Show Donor Effects Over PMOS Signal in 14-Line Study

A 14-line iPSC study found donor-to-donor variation outweighed PMOS status, with no robust disease transcriptome and possible XIST…

2 days ago

Endocrinology·KFF

FDA Adds Rare Blindness Warning to GLP-1 Drug Labels

FDA is requiring GLP-1 labels to warn about a rare sudden-blindness risk, raising new counseling and monitoring duties…

2 days ago

Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.