Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

Fibrous Dysplasia and McCune-Albright Syndrome: Advances in Pathogenesis Research

A 2025 review outlines GNAS-driven pathology in fibrous dysplasia/McCune-Albright syndrome and the unresolved biology behind severe skeletal disease.

Hospitals and ambulance services face disruption after a ketone test strip recall, with guidance to protect patients at…

A NEJM letter contrasts TRANSCEND trial reporting with FDA approval data for setmelanotide in acquired hypothalamic obesity, including…

Organotypic vascularization improved maturation of human stem cell-derived islets and restored normoglycemia in diabetic mice, pointing to a…

OMass secured $310 million to advance OMS1620, a small-molecule MC2 receptor blocker for congenital adrenal hyperplasia and Cushing’s…

Mouse data show FGF21 and soluble TGFBR2 can improve metabolic dysfunction in lipodystrophy, with efficacy shaped by housing…

FDA approves the first generic once-weekly estradiol and levonorgestrel patch for menopausal symptoms and osteoporosis prevention in women…

A controlled audit of the ann-thyroid benchmark found class labeling and imbalance drove performance more than algorithm choice…

Young rats exposed to food insecurity developed sex- and diet-specific metabolic changes, with male HF/HS-fed animals showing greater…

A case report examines primary hyperparathyroidism presenting as a rare hypercalcemic crisis and the diagnostic delays that can…

Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

In Brief The 5-minute rounds