Dutch emergency department patients describe mixed feelings about opioid prescribing at discharge

In Dutch emergency departments, opioid prescribing at discharge is not just a prescribing decision. It is also a conversation about pain, function, safety, and what patients expect when they leave the hospital.

A qualitative interview study examined the experiences and perspectives of patients who had visited emergency departments in the Netherlands and received an opioid prescription at discharge. The work focused on how patients viewed opioid use and opioid misuse in the emergency setting, a setting where clinicians often have to balance short-term analgesia against the risk of persistent use and other harms.

The study drew on semi-structured interviews and included patients from both an academic and a non-academic emergency department. Participants had been prescribed different types of opioids and presented with a range of clinical complaints, giving the analysis a broader view of how people respond to opioid prescribing across routine emergency care. One participant was already using opioids at the time of the emergency department visit, but the cohort otherwise offered limited insight into patients with established chronic opioid exposure.

What patients bring to the decision at the bedside

Emergency department discharge is a fragile moment in the care pathway. Patients are often in pain, tired, and trying to make sense of what happens next. In that setting, an opioid prescription can feel reassuring, but it can also carry uncertainty. The interviews were designed to capture those patient-facing tensions rather than rely on clinician assumptions about why opioids are accepted, questioned, or resisted.

A qualitative approach is especially suited to this problem because prescribing decisions are rarely driven by pharmacology alone. The lived experience of pain, prior exposure to pain medication, fear of side effects, and personal beliefs about dependence all shape whether an opioid feels like a necessary bridge home or a drug that should be used cautiously. Reflexive thematic analysis allowed the researchers to turn those narratives into themes through independent coding by two researchers and discussion in multidisciplinary analytic meetings.

This design matters because emergency physicians often see the prescription as a brief intervention, while patients may experience it as part of a larger story about pain control, trust, and vulnerability. Oral opioids can reduce acute pain, but they also introduce risks that become more relevant once the patient leaves the controlled environment of the emergency department. Even without chronic opioid use in most participants, the interviews offer a useful window into how people understand that tradeoff in real time.

Why acute pain care and opioid risk remain difficult to separate

The central clinical challenge is simple to state and difficult to solve: acute pain must be treated, but opioid exposure should not become routine when safer options may suffice. In emergency medicine, the pressure to relieve suffering immediately can push treatment toward faster, stronger analgesia, particularly when a patient is discharged before symptom resolution.

At the same time, population-level concerns about prescription opioid harm have changed the stakes of everyday discharge prescribing in many countries. The background to this study reflects that shift, with rising prescription opioid use in Western countries and severe opioid-related harm in some settings, including high mortality and major societal costs. The Dutch context is different from the United States, but the clinical question remains familiar: how do patients understand an opioid prescription that is intended for short-term relief yet still carries the possibility of misuse, adverse effects, or prolonged use?

The interviews were built to address precisely that kind of uncertainty. Patients’ perspectives can reveal whether they see opioids as necessary medicine, last-resort therapy, something to avoid, or a treatment they accept without much discussion because they are focused on discharge and relief. Those impressions shape adherence, storage, disposal, and future expectations about pain treatment. They also influence whether patients return with lingering symptoms, modify the dose on their own, or avoid using the medication entirely.

The qualitative design provides context the prescription itself cannot

Because this was a qualitative study, the value lies less in numerical endpoints than in the texture of the patient narratives. The investigators used semi-structured interviews, then coded transcripts independently before refining the thematic structure in multidisciplinary meetings. That process strengthens the interpretive quality of the work and makes the findings more useful for clinicians who need to understand how patients interpret opioid prescribing in practice.

The diversity of emergency department setting also adds practical relevance. Academic and non-academic hospitals do not always deliver care in the same way, and discharge counseling can vary depending on local protocols, clinician experience, and patient population. Including both types of site gives the analysis a wider clinical frame, even though the study remains limited by its small qualitative scope and the narrow representation of patients with current chronic opioid use.

One sentence from the study design stands out: transferability to patients with ongoing chronic opioid use may be limited. That is not a minor caveat. It means the findings are best used to understand opioid prescribing in acute emergency care rather than to generalize across all opioid-exposed patients.

What emergency clinicians can take from this study

For emergency clinicians, the practical implication is straightforward even if the underlying behavior is complex. Opioid prescribing at discharge is not only a medication choice; it is a communication event. Patients need to understand why an opioid is being offered, how long it should be used, what side effects to expect, and when to stop.

The study also reminds clinicians that patient perspectives are not interchangeable with clinician risk models. A prescription that seems modest from the prescriber’s point of view may be interpreted by a patient as a sign that severe harm is present, or, in some cases, as proof that nothing else will work. Either reaction can shape future care-seeking behavior and medication use.

Acute pain treatment in the emergency department will always require judgment. The challenge is to preserve analgesic benefit without normalizing unnecessary opioid exposure, especially at discharge when supervision ends and self-management begins. This qualitative work does not provide a prescribing algorithm, and it does not claim to define the ideal opioid strategy. It does show that patient experience belongs inside the prescribing conversation, not after it.

Limits of transferability and the need for broader patient voices

The most important limitation is the narrow representation of patients already living with chronic opioid use. In a field where long-term exposure, tolerance, dependence, and prior treatment failures can strongly shape beliefs about analgesia, that gap matters for interpretation. The findings are strongest for patients receiving opioids around an acute emergency department visit, not for those with established opioid treatment histories.

Even so, the study fills a useful gap in emergency medicine. Prescribing debates often focus on clinician behavior, policy restrictions, or population harm statistics. Those are essential, but they do not replace the patient perspective. Interviews from Dutch emergency departments add a grounded view of how people experience opioid prescribing at the moment it happens, when pain relief, fear, relief, and uncertainty may all be present at once.

Future work will need to expand the patient mix and examine how perspectives differ among people with repeated opioid exposure, long-term pain, or prior negative experiences with analgesics. Until then, this study offers a clear reminder that discharge prescribing decisions are judged not only by clinical appropriateness but by how patients live with them after they leave the emergency department.


Reporting by Dr. A. Nikhil Krishnan, MBBS for Medicine World Foundation, with additional data provided by BMJ Open.