Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

Dietary Fatty Acids Shape Osteoarthritis Risk After Joint Injury

In obese mice, dietary fatty acid composition—not body weight—shaped osteoarthritis severity, wound repair, synovitis, and fibrosis after joint injury.

By Dr. A. Nikhil Krishnan, MBBS · Oct 18, 2026 · 5 min read

Rheumatology·ARD

KLF2 enhancer variant rs4808485 linked to lupus risk through inflammasome control

A KLF2 enhancer variant, rs4808485, appears to raise lupus risk by altering KLF2 expression, inflammasome signaling, and immune…

Oct 18, 2026

Rheumatology·Lan GH

CAR T Cells in Autoimmune Disease: 2026 EBMT-ISCT-JACIE Update

Updated expert consensus refines CAR T cell use in severe autoimmune disease, covering patient selection, monitoring, follow-up, and…

Oct 18, 2026

Rheumatology·Brain

B cell depletion in SLE: patient selection, timing and next therapies

A rheumatology review explains why B cell depletion works in SLE, where anti-CD20 therapy falls short, and which…

Oct 18, 2026

Rheumatology·Brain

Mixed Connective Tissue Disease Study Examines Severity Classification

A nationwide retrospective study in Mixed Connective Tissue Disease examines clinical features and how severity may be classified…

Oct 18, 2026

Rheumatology·Lancet

Korean Rheumatology Updates Axial Spondyloarthritis Treatment Recommendations

Korean College of Rheumatology updates axSpA guidance with treat-to-target care, NSAIDs first, and biologic or JAK inhibitor sequencing.

Oct 18, 2026

Rheumatology·NEJM

Obinutuzumab Improves Active SLE Responses in Phase 3 Trial

Phase 3 trial data show obinutuzumab improved SRI-4 responses in active SLE, with a safety profile consistent with…

Oct 18, 2026

Rheumatology·ARD

Rheumatoid Arthritis Pain and Prognosis Frame Annals Abstract Session

A scraped Annals of the Rheumatic Diseases abstract session centers on rheumatoid arthritis pain and prognosis, but no…

Oct 18, 2026

Rheumatology·ScienceDaily

CAR T-Cell Therapy Puts Severe Rheumatoid Arthritis Into Remission

In a first-in-human trial, CD19 CAR T-cell therapy drove remission in severe rheumatoid arthritis and may reset pathogenic…

Oct 18, 2026

Rheumatology·JCI

SLE signature found in resting naive B cells in inactive disease

Resting naive B cells in systemic lupus erythematosus carried a distinct disease signature, even in inactive disease, with…

Oct 18, 2026

Rheumatology

Trials, guidelines and clinical evidence across Rheumatology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.