Psychiatry

Clinical evidence, research, and medical intelligence in Psychiatry.

GlycoRNA-Microglial Coupling Linked to MDD in Prefrontal Cortex Study

Postmortem DLPFC data suggest GlycoRNA pathway enrichment tracks microglial signatures more strongly than other cell types in controls, with attenuation in MDD.

By Dr. A. Manasa, MBBS · Oct 19, 2026 · 5 min read

Psychiatry·JAMA IM

GLP-1 Agonists Linked to Neuropsychiatric Signals in New Review

A Bradford Hill-informed review examines whether GLP-1 and dual GIP/GLP-1 agonists may influence mood, cognition, suicidality, and reward…

Oct 19, 2026

Psychiatry·BBC Dental

Presley Gerber death under overdose investigation after rehab facility death

Presley Gerber’s death at 27 is being investigated as a suspected overdose after he died at a California…

Oct 19, 2026

Psychiatry·Lan D&E

Youth Mental Health Research in Africa Lacks Full Article Context

Source material contains only the article title, with no abstract or study data available to support a clinical…

Oct 19, 2026

Psychiatry·JAMA

Caring Letters After Veteran Crisis Line Calls Did Not Reduce Suicide Attempts

In veterans who contacted the Veterans Crisis Line, caring letters did not lower suicide attempts but were linked…

Oct 19, 2026

Psychiatry·Lancet

Treatment-resistant PTSD definitions remain inconsistent across studies

A systematic review found wide variation in treatment-resistant PTSD definitions and calls for a dynamic framework using adherence,…

Oct 19, 2026

Psychiatry·DailyMed

Trazodone Label Update Flags Suicidality, QT Risk, and Serotonin Syndrome

Updated trazodone labeling details boxed suicidality warning, dosing, QT prolongation, serotonin syndrome, orthostasis, and key interactions.

Oct 19, 2026

Psychiatry·medRxiv

Youth Depression Screening Gets 5-Item Short Forms for Faster Assessment

Five-item versions of common youth depression scales matched full measures closely and identified depression with fair-to-good accuracy in…

Oct 19, 2026

Psychiatry·Lan Heme

Antipsychotic initiation linked to rapid HbA1c and weight rise in England study

Large English EHR analysis found rapid HbA1c and weight increases after antipsychotic start, with greatest early metabolic change…

Oct 19, 2026

Psychiatry·ScienceDaily

Deep brain stimulation study maps 3 pathways tied to depression relief

Mount Sinai researchers linked lasting depression relief from deep brain stimulation to three white matter pathways and identified…

Oct 19, 2026

Psychiatry

Clinical evidence, research, and medical intelligence in Psychiatry.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.