Orthopedics

Clinical evidence, research, and medical intelligence in Orthopedics.

Vitex negundo extract boosts osteogenic markers and antibacterial activity in vitro

Vitex negundo leaf aqueous extract increased osteogenic markers, mineralization, and antibacterial activity in SaOS-2 cells and against two pathogens.

By Dr. A. Nikhil Krishnan, MBBS · Oct 25, 2026 · 5 min read

Orthopedics·NIH

Metagenomic Sequencing in Prosthetic Joint Infection Draws Clinical Scrutiny

A systematic review and meta-analysis examines metagenomic next-generation sequencing for prosthetic joint infection, with attention to accuracy and…

Oct 25, 2026

Orthopedics·bioRxiv

Spontaneous OA in CD1 Mice Shows Whole-Joint Disease Progression

A preprint characterizes spontaneous osteoarthritis in CD1 mice, finding age-related cartilage loss, ligament remodeling, and gastrocnemius atrophy.

Oct 25, 2026

Orthopedics·ClinicalTrials

Trochanteric Bursa Repair Trial Targets Lateral Hip Pain After Hemiarthroplasty

A randomized trial will test whether repairing the trochanteric bursa lowers early lateral hip pain after hemiarthroplasty for…

Oct 24, 2026

Orthopedics·BMJ

Primary Cam Morphology Consensus Sets Research Priorities for Young Hips

International experts ranked 18 priorities for primary cam morphology and femoroacetabular impingement syndrome, focusing on rehab, prognosis, diagnosis,…

Oct 24, 2026

Orthopedics·Med News Today

Crunching Sound in Neck: Common Causes, Diagnosis, and Care

Neck crunching is often harmless, but pain, stiffness, swelling, or numbness can signal injury, arthritis, or spinal disease.

Oct 24, 2026

Orthopedics·Nature

Social alienation model in adolescent idiopathic scoliosis identifies high-risk trajectories

A prospective cohort study in adolescent idiopathic scoliosis identified three social alienation trajectories and a seven-factor prediction model…

Oct 24, 2026

Orthopedics·BMJ

Robotic Knee Replacement Costs Draw Scrutiny in BMJ Response

A BMJ rapid response questions whether robotic knee replacement cost estimates used private tariffs rather than NHS resource…

Oct 24, 2026

Orthopedics·BMJ

Robotic knee replacement data still blur platform and alignment effects

BMJ commentary says robotic knee replacement data mix platform, alignment, and soft-tissue effects, limiting claims of added clinical…

Oct 24, 2026

Orthopedics·Cancer Cell

Meniscus Scaffold Restores Zonal Fibrochondrogenic and Angiogenic Gradients

A zonally patterned DBM-meniscus ECM scaffold directed region-specific fibrochondrogenic and angiogenic responses in preclinical meniscus repair work.

Oct 24, 2026

Orthopedics

Clinical evidence, research, and medical intelligence in Orthopedics.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.