Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

IBD Cancer Study Links CXCL14 Fibroblasts to Fibrosis and Tumorigenesis

Single-nuclei and spatial analyses trace IBD-associated cancer to CXCL14+ fibroblasts, collagen IV, and SPP1+ macrophages.

By Dr. Revathy Mohan V.R., MBBS · Oct 22, 2026 · 5 min read

Oncology·ESMO Open

Proteogenomics study maps survival-linked signatures in ovarian cancer

ESMO Open abstract describes integrative proteogenomics in high-grade serous ovarian cancer, linking survival, co-expression modules, and HR activity.

Oct 22, 2026

Oncology·ESMO Open

Glycolysis Inhibition Targets HNF-1β-Positive Clear Cell Carcinoma

ESMO Open describes a metabolic approach that combines glycolysis inhibition and mitochondrial biogenesis to trigger ROS-dependent cell death…

Oct 22, 2026

Oncology·ESMO Open

Cancer Prevention Drug Trials Succeed When Biology and Evidence Align

A review of 92 phase III cancer prevention trials found higher success with targeted drugs, strong prior evidence,…

Oct 22, 2026

Oncology·medRxiv

Oesophageal Adenocarcinoma Genomic Markers Linked to Survival After Surgery

A 65-patient surgery-only cohort links CCND1 and EGFR amplification, ARID2 loss, and RYR1 mutation to worse survival in…

Oct 22, 2026

Oncology·ClinicalTrials

Breast Cancer Study Tests Whether Cognitive Impairment Fuels Chronic Pain

A prospective breast cancer cohort will test whether chemotherapy-related cognitive impairment predicts chronic pain over 12 months after…

Oct 22, 2026

Oncology·PLOS Med

Same-Day Idylla PCR Cuts Molecular Turnaround in Lung Cancer Testing

PLOS One data show same-day Idylla PCR could shorten actionable lung cancer results by nearly 19 days versus…

Oct 22, 2026

Oncology·NEJM

AAV Integration in Paraspinal Neoplasm Raises Gene Therapy Safety Questions

NEJM letter describes AAV integration in a paraspinal neoplasm after gene therapy, with retained promoter-enhancer activity driving a…

Oct 22, 2026

Oncology·JCO

Patient Navigation Can Address Survivorship Needs in Cancer Care

A scoping review found patient navigation improved survivorship support, psychosocial outcomes, and care coordination across diverse cancer populations.

Oct 22, 2026

Oncology·BBC Dental

Brain cancer funding push grows after child’s ependymoma death

A grieving family backs new brain cancer funding promises after their four-year-old daughter died following surgery and proton…

Oct 22, 2026

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.