Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

RPT04402 Restores PP2A Signaling in High-Grade Uterine Cancer

RPT04402, a molecular glue, restores PP2A trimer formation in high-grade uterine cancer, pointing to a new translational target in tumor signaling.

China’s procurement policy improved affordability and generic uptake for some childhood leukemia TKIs, especially imatinib, in children’s hospitals.

A review explains how epithelial stem cell competition, environmental exposure, and selected mutations shape normal tissue and cancer…

Belfast’s planned haematology centre has been delayed after the Health Department withdrew £1.5m, raising concerns for immunocompromised cancer…

Researchers identified gamma delta T cells that attack small cell lung cancer and may be boosted by existing…

IARC and partners say socioeconomic inequalities in cancer mortality are widespread in Europe and could be reduced with…

Single-cell multiomics links complement-secreting CAFs with longer survival in pancreatic cancer and suggests a path to fibroblast reprogramming.

The scraped abstract is incomplete, leaving no usable methods or results to assess EGFR amplification, panitumumab, or trial…

Peak cilta-cel expansion was associated with delayed neurotoxicity in multiple myeloma, raising concerns about exposure, kinetics, and CNS…

A retrospective All of Us cohort study examines liver fibrosis risk, missed follow-up, and inequitable specialist referral patterns.

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds