Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Tirzepatide Trial Targets Cardiotoxicity in Young Sarcoma Survivors

MD Anderson is testing tirzepatide in overweight and obese young sarcoma survivors to assess feasibility, safety, and early cardiac and metabolic effects.

By Dr. Revathy Mohan V.R., MBBS · Oct 23, 2026 · 6 min read

Oncology·Blood

AML targeted therapy shows no survival disparity across racial groups

Real-world AML outcomes were similar across racial and ethnic groups receiving FLT3, IDH1, or IDH2 targeted TKI therapy…

Oct 23, 2026

Oncology·JCO

Belantamab Mafodotin Quadruplet Tested in Newly Diagnosed Myeloma

Phase 1/2 BelaDRd study evaluates belantamab mafodotin with daratumumab, lenalidomide, and dexamethasone in transplant-ineligible myeloma.

Oct 23, 2026

Oncology·JCO

Immune Checkpoint Inhibitor Adoption and Survival in Lung Cancer Cohort

Urban lung cancer cohort study examined immune checkpoint inhibitor use, treatment timing, and survival with a landmark analysis…

Oct 23, 2026

Oncology·JCO

Intradural Spine Metastases Study Examines Molecular and Clinical Features

JCO abstract focuses on systemic cancers that spread to the intradural spine, a rare and clinically urgent metastatic…

Oct 23, 2026

Oncology·DailyMed

Tecentriq Hybreza label expands across lung and solid tumors

DailyMed label update details Tecentriq Hybreza dosing, indications, and safety warnings across NSCLC, SCLC, HCC, melanoma, and more.

Oct 23, 2026

Oncology·DailyMed

Ifosfamide label warns of severe marrow, kidney, bladder toxicity

DailyMed’s updated ifosfamide label reinforces boxed warnings for marrow suppression, encephalopathy, renal injury, and hemorrhagic cystitis.

Oct 23, 2026

Oncology·Cancer Cell

Multiple Myeloma Genomics Links Germline Risk to Clonal Evolution

A genomic framework for multiple myeloma connects inherited susceptibility, founding lesions, and treatment-driven clonal evolution to future risk…

Oct 23, 2026

Oncology·Cancer Cell

EpCAM-linked membrane mechanics tied to gastric cancer metastasis

EpCAM-dependent membrane mechanics were linked to nuclear deformation and gastric cancer metastasis in a Cell Press study of…

Oct 23, 2026

Oncology·medRxiv

p53-Abnormal Early-Stage Endometrial Cancer Recurrence Favors Chemotherapy

Early-stage endometrioid endometrial cancer with p53-abnormality showed mostly distant recurrences, and chemotherapy trended better than radiation-based adjuvant therapy.

Oct 23, 2026

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.