Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

TAK-243 CRISPR Screen Identifies HAPSTR1/HUWE1 Chromatin Axis

A Science study links TAK-243 screening to the HAPSTR1/HUWE1 axis, pointing to new control points in chromatin proteostasis and cell-cycle regulation.

By Dr. Revathy Mohan V.R., MBBS · Oct 24, 2026 · 5 min read

Oncology·EHJ

Cancer Progression Risk by HIV Status Requires Careful Real-World Design

An Oxford Academic review examines how real-world comparisons estimate cancer progression risk by HIV status and why interpretation…

Oct 24, 2026

Oncology·JCO

Hepatocellular Carcinoma Study Examines BET Inhibition in PD-1 Resistance

Preclinical murine work in hepatocellular carcinoma examines BET bromodomain inhibition as a strategy to probe acquired PD-1 resistance.

Oct 24, 2026

Oncology·JCO

CAR-T Therapy Faces AML and Solid Tumor Barriers

A review explains why CAR-T works in B-cell cancers but remains difficult in AML and solid tumors, with…

Oct 24, 2026

Oncology·JCO

Sunvozertinib first-line NSCLC trial targets EGFR exon20ins

First-line sunvozertinib monotherapy was compared with platinum-based chemotherapy in advanced NSCLC with EGFR exon20ins, addressing a difficult treatment…

Oct 24, 2026

Oncology·Nature

Transformer U-Net improves breast ultrasound lesion analysis

Hybrid deep learning models for breast ultrasound analysis delivered strong classification and segmentation performance in patient-separated cross-validation.

Oct 24, 2026

Oncology·PubMed

EGFR-targeted antibody-toxin conjugate shows activity in recurrent glioma

A phase 1 trial found D2C7-ATC was tolerable in recurrent glioma and linked EGFR-related biomarkers with longer survival…

Oct 24, 2026

Oncology·STAT

Urological Cancers Review Maps PI3K, mTOR and PD-1 Targets

A 2026 review maps PI3K/Akt, mTOR, c-Met, PD-1/PD-L1 and hormone pathways shaping resistance and precision therapy in urological…

Oct 24, 2026

Oncology·Cancer Cell

Breast Cancer Six-Gene Prognostic Signature Tied to Tumor Microenvironment

A breast cancer study identified and validated a six-gene prognostic signature linked to tumor microenvironment features, pointing to…

Oct 24, 2026

Oncology·Nature

Lung Cancer Classification Model Combines Deep CNNs and Random Forest

A hybrid AI framework using DenseNet169, MobileNetV2, and random forest classified thoracic CT scans with high accuracy and…

Oct 24, 2026

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.