Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

Gastric Cancer 3D Staging Improves Prognosis After Neoadjuvant Therapy

A multicenter study in locally advanced gastric cancer found a new TRG-ypT-ypN 3D staging model outperformed ypTNM, especially after immunochemotherapy.

By Dr. Revathy Mohan V.R., MBBS · Nov 3, 2026 · 5 min read

Oncology·JAMA Onc

Surveillance Mammography Did Not Lower Advanced Second Breast Cancer Risk in Older Survivors

In older breast cancer survivors, continued surveillance mammography was not linked to fewer advanced second primary cancers, and…

Nov 3, 2026

Oncology·Cancer Disc

ETx-22 Shows Antitumor Activity in Low Nectin-4 Tumors

ETx-22, a nectin-4 antibody-drug conjugate with an exatecan payload, produced durable activity in low-target tumors and a better…

Nov 3, 2026

Oncology·Lancet Onc

Proteome-Based Classification Reshapes Pediatric Adrenocortical Tumor Biology

A proteome-based study in pediatric adrenocortical tumors links functional tumor states with outcome and therapeutic vulnerabilities.

Nov 3, 2026

Oncology·BBC Dental

Prostate Cancer Survivor to Trek Sahara for Better Testing

A 75-year-old prostate cancer survivor will trek 100km across the Sahara to raise money for improved testing and…

Nov 3, 2026

Oncology·Becker H

Cancer vaccines gain ground after melanoma phase 3 success

A phase 3 melanoma trial gave personalized cancer vaccines their first clear benefit, but manufacturing, cost and access…

Nov 3, 2026

Oncology·JCI

Rituximab May Reduce Checkpoint Toxicity in Advanced Melanoma

A small randomized melanoma trial found rituximab cut severe checkpoint toxicities without obvious loss of antitumor activity, but…

Nov 3, 2026

Oncology·JCI

Source article body missing for JCI lung tumor immunotherapy study

The scraped input includes only the title and metadata, not the Results or Methods needed for a faithful…

Nov 3, 2026

Oncology·JCI

Renal Cell Carcinoma Study Links TARBP2 to Immune Escape Pathway

A JCI study examines how TARBP2 may drive renal cell carcinoma immune escape through 53BP1 phase separation and…

Nov 3, 2026

Oncology·JCI

B Cell Depletion Cuts Severe irAEs in Advanced Melanoma Checkpoint Therapy

Rituximab given with ipilimumab and nivolumab lowered severe immune toxicity in advanced melanoma without an obvious drop in…

Nov 3, 2026

Oncology

Therapeutics, diagnostics and evidence shaping cancer care.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.