Neurology

From stroke to neurodegeneration — the science and its clinical impact.

Intranasal insulin does not reduce amyloid in 5xFAD mice

Synchrotron imaging in 5xFAD mice found intranasal insulin did not lower plaque burden but altered ileal structure and fecal protein profiles.

By Dr. A. Manasa, MBBS · Oct 22, 2026 · 5 min read

Neurology·PLOS ONE

Uganda stroke burden rises steadily through 2028 forecast

National DHIS2 data show rising stroke cases and deaths in Uganda, with projections through 2028 pointing to worsening…

Oct 22, 2026

Neurology·Nat Rev Onc

APOE ε4 accelerates Alzheimer plasma biomarker shifts with age

In 5,913 adults, APOE ε4 status intensified age-related plasma biomarker changes linked to preclinical Alzheimer pathology, especially p-tau217.

Oct 22, 2026

Neurology·Nat Rev Onc

Glucocorticoids Linked to Better Outcomes After Flow Diverter Aneurysm Repair

Low-dose perioperative glucocorticoids were associated with fewer cerebrovascular events and less in-stent stenosis after flow diverter treatment of…

Oct 22, 2026

Neurology·BMJ Open

Primary Care Headache Management Centers on Comorbidity-Aligned Therapy

A BMJ Open review outlines primary care headache treatment strategies that match therapy to comorbidities, limit polypharmacy, and…

Oct 21, 2026

Neurology·PNAS

HIV-1 Infection of Neural Xenografts Reveals Monocyte-Driven Brain Injury

A rat xenograft model showed HIV-1 sequences in human neural tissue, with injury concentrated in grafts exposed to…

Oct 21, 2026

Neurology·Nature

Psilocybin plasticity depends on layer 5 5-HT2A receptors, study finds

Mouse data link psilocybin’s synaptic remodeling to layer 5 5-HT2A receptors, separating plasticity from hallucination-like behavior.

Oct 21, 2026

Neurology·Nature

Multiple sclerosis study links periventricular damage to ependymal dysfunction

Ultra-high-field MRI, histology, and single-nucleus multiomics connect periventricular MS gradients to reactive ependyma and disrupted adhesion.

Oct 21, 2026

Neurology·Med News Today

Ultra-processed foods linked to MRI signs of brain injury in adults

A Canadian study links higher ultra-processed food intake to MRI signs of brain injury in healthy adults, with…

Oct 21, 2026

Neurology·BMJ Open

High-density CSD arrays can distort signal interpretation, study finds

High-density current source density arrays can blur sinks and sources, distorting interpretation unless reconstruction parameters are tuned carefully.

Oct 21, 2026

Neurology

From stroke to neurodegeneration — the science and its clinical impact.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.