Nephrology

Renal disease, dialysis, transplantation and electrolyte disorders.

NK Cell Biomarker Signals Kidney Transplant Graft Dysfunction Risk

High-dimensional NK cell profiling linked donor-reactive Ksp37 release and Ksp37 expression to poorer kidney transplant outcomes beyond antibody injury.

By Dr. A. Nikhil Krishnan, MBBS · 7 days ago · 5 min read

Nephrology·Nature

Imipenem/cilastatin does not lower AKI risk in ICU carbapenem therapy

Three ICU databases found no overall acute kidney injury benefit from imipenem/cilastatin versus other carbapenems in critically ill…

Nov 6, 2026

Nephrology·Kidney Int

Alport Syndrome Genetic Prevalence Reassessed After In Silico Overestimation

A reevaluation of COL4A3 and COL4A4 variant curation suggests prior estimates of Alport syndrome prevalence may have been…

Nov 6, 2026

Nephrology·JNCI

Corticosteroids and Serum Proteins in IgA Nephropathy Precision Care

An editorial examines how corticosteroids and serum proteins may shape the next phase of precision medicine in IgA…

Nov 6, 2026

Nephrology·Front Immunol

Hemodialysis Linked to T-Cell Activation in ESRD Patients

Flow cytometry found hemodialysis in ESRD was associated with greater T-cell activation and higher IFN-γ secretion than pre-dialysis…

Nov 6, 2026

Nephrology·Front Immunol

Pyroptosis in CKD: renal inflammatory target moves toward translation

A Frontiers in Immunology review maps pyroptosis in CKD, separating human evidence from preclinical data and outlining emerging…

Nov 6, 2026

Nephrology·Cancer Cell

JAK Inhibition Shows Activity in Refractory Membranous Glomerulopathy Case

A case report describes JAK inhibition in therapy-refractory full-house membranous glomerulopathy linked to type I interferon activation and…

Nov 5, 2026

Nephrology·MedCity

Mount Sinai Gets $4M NIH Grant for AI Kidney Injury Prediction

Mount Sinai will use a $4 million NIH grant to build AI models that predict postoperative acute kidney…

Nov 5, 2026

Nephrology·BMJ Open

OK-TRANSPLANT 2 tests semaglutide-based weight care in advanced CKD

BMJ Open protocol describes a pragmatic randomized trial of semaglutide-based obesity care for adults with advanced CKD and…

Nov 5, 2026

Nephrology·JCI

PLA2R Epitope Pairing Drives Complement Activation in Membranous Nephropathy

Patient-derived PLA2R antibodies triggered complement in membranous nephropathy when epitope pairings and IgG subclass combinations aligned.

Nov 4, 2026

Nephrology

Renal disease, dialysis, transplantation and electrolyte disorders.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.