Hepatology

Clinical evidence, research, and medical intelligence in Hepatology.

Aerobic exercise boosts MOTS-c to ease MASLD in mice

Aerobic exercise restored skeletal muscle MOTS-c and raised hepatic ACE2 in MASLD mice, reducing steatosis, inflammation, and metabolic dysfunction.

MASLD affects at least one-quarter of the population and is tied to cardiovascular disease, CKD and cancer risk,…

GSK has terminated phase 1 development of GSK3965193, even as bepirovirsen gains FDA approval for chronic hepatitis B.

Journal of Hepatology clarification explains Table 3 denominators for ELM score zones and corrects two numerical reporting errors…

FDA approves Hibsago, the first antisense oligonucleotide for chronic hepatitis B, for selected adults without cirrhosis on antiviral…

Human liver cells metabolise and present MAIT-stimulatory antigens, while serum from portal blood and IBD patients activates MAIT…

A review links MASLD and MASH to cardiac and renal injury through hepatokines, inflammation, and metabolic therapies including…

A case report links long-term denosumab exposure with autoimmune hepatitis in a patient with Hashimoto thyroiditis, raising safety…

A long-term PAGE-B cohort in chronic hepatitis B examined HCC risk and HBsAg clearance after more than 10…

Mayo Clinic researchers identified five biologically distinct MASLD subtypes, each tied to different risks for liver failure, cancer,…

Hepatology

Clinical evidence, research, and medical intelligence in Hepatology.

In Brief The 5-minute rounds