Hematology

Trials, guidelines and clinical evidence across Hematology.

Occult lymphoma drives HLH in 38-year-old woman despite negative imaging

A 38-year-old woman with HLH had occult peripheral T-cell lymphoma found only after PET-CT guided tonsillar biopsy and treatment.

By Dr. Revathy Mohan V.R., MBBS · Oct 20, 2026 · 5 min read

Hematology·Nat Immunol

Clonal hematopoiesis may persist in fibrotic bone marrow niches

Bone marrow fibroblast-rich inflammatory pockets may help clonal hematopoiesis cells survive, revealing a niche-driven route to disease persistence.

Oct 19, 2026

Hematology·Front Immunol

Sirolimus Shows Add-On Activity in Refractory iMCD-TAFRO Case Series

Eight refractory iMCD and TAFRO patients received add-on sirolimus, with responses, steroid withdrawal, dialysis discontinuation, and paired single-cell…

Oct 19, 2026

Hematology·CID

ASFA therapeutic apheresis guideline updates 183 graded indications

ASFA’s 2026 special issue updates therapeutic apheresis guidance with 93 fact sheets, 183 graded indications, and revised evidence…

Oct 19, 2026

Hematology·Gut

Decentralized CAR-T Manufacturing Could Expand Access and Cut Costs

A WBMT review examines point-of-care CAR-T manufacturing, shorter vein-to-vein times, lower production costs, and the regulatory hurdles to…

Oct 19, 2026

Hematology·Nat Immunol

CHIP reshapes bone marrow with fibro-inflammatory remodeling in new study

Single-cell and spatial profiling shows clonal hematopoiesis expands fibroblasts and inflammatory hubs in bone marrow, linking CHIP to…

Oct 19, 2026

Hematology·Cochrane

Statins for First Venous Thromboembolism Under Cochrane Review

Cochrane review examines statins for adults after a first venous thromboembolic event, an area with unresolved treatment questions.

Oct 19, 2026

Hematology·Front Immunol

PB CD34+ peak predicts neutrophil engraftment after autologous HSCT

Peripheral blood CD34+ peak during mobilisation independently predicted neutrophil engraftment after autologous HSCT in a cohort of 302…

Oct 19, 2026

Hematology·JNCI

Therapeutic Apheresis Guidelines Updated in ASFA Tenth Special Issue

ASFA’s Tenth Special Issue updates therapeutic apheresis recommendations with 93 fact sheets and 183 graded indications across many…

Oct 19, 2026

Hematology·Blood

Germline DDX41 Marks Distinct MDS Subgroup With Better Transplant Outcomes

Germline DDX41 identifies a distinct MDS subgroup undergoing transplantation, with lower relapse and improved survival in the study…

Oct 18, 2026

Hematology

Trials, guidelines and clinical evidence across Hematology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.