Genetics

Clinical evidence, research, and medical intelligence in Genetics.

Adult Genetic Medicine Delivers High Diagnostic Yield Across 10,000 Visits

Eight years of adult genetics clinic data show substantial diagnostic yield, strong exome performance, and large variation by indication and test type.

By Dr. A. Nikhil Krishnan, MBBS · Oct 24, 2026 · 5 min read

Genetics·Cancer Cell

Olfactory receptor gene loss links giant panda and marine carnivores

A comparative genomics study examines similar olfactory receptor gene degeneration in the giant panda and marine carnivores.

Oct 23, 2026

Genetics·Cancer Cell

Female iPSC X Inactivation Erosion During CRISPR Editing and Neural Differentiation

Cell Press study examines X chromosome inactivation erosion in female iPSCs and its transcriptomic effects during CRISPR editing…

Oct 23, 2026

Genetics·NLM Alerts

NIH Genetic Testing Registry centralizes test data to improve transparency

The NIH Genetic Testing Registry centralizes voluntary data on genetic tests, including validity, utility, methods, and laboratory details…

Oct 23, 2026

Genetics·BMJ

NHS genomics labs lag on ClinVar data sharing for rare disease care

Three NHS Genomics Laboratory Hubs are not routinely submitting variants to ClinVar, delaying reclassification, diagnosis, and rare disease…

Oct 22, 2026

Genetics·Cancer Cell

Chicken HSF5 Duplication Linked to Transcript Remodeling and Triple-Comb Morphology

A tandem duplication upstream of HSF5 in chickens is linked to transcript remodeling and a distinctive triple-comb morphology…

Oct 22, 2026

Genetics·Cancer Cell

Explainable AI guides EastFocus AISNPplex 61 ancestry assay design

Cell Press describes an explainable AI approach to marker selection for EastFocus AISNPplex 61, aimed at fine-scale biogeographical…

Oct 22, 2026

Genetics·MedlinePlus

Microphthalmia with Linear Skin Defects Syndrome Linked to X Chromosome Loss

Microphthalmia with linear skin defects syndrome causes eye maldevelopment and linear skin changes, usually from X chromosome loss…

Oct 21, 2026

Genetics·Nature

Base editors move from bench to clinic after a decade of progress

A Nature Medicine review traces a decade of base editing advances, from cytosine editors to clinical trials in…

Oct 21, 2026

Genetics·Cancer Cell

Deep learning maps genetic variation affecting transcription factor binding in embryogenesis

A Drosophila study combines haplotype testing and Basenji to pinpoint variants that alter transcription factor binding during embryogenesis.

Oct 21, 2026

Genetics

Clinical evidence, research, and medical intelligence in Genetics.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.