Gastroenterology

Digestive disease, hepatology, endoscopy and inflammatory bowel disease.

Barrett’s Oesophagus Trials Cluster Around Reflux, Screening, and Surveillance

A systematic mapping review found most registered Barrett’s oesophagus and reflux trials focused on alternative reflux treatments, screening, and surveillance.

By Dr. A. Nikhil Krishnan, MBBS · 3 days ago · 6 min read

Gastroenterology·Gut

ForePass tops semaglutide in swine insulin sensitivity and weight control

In a 30-day swine study, ForePass beat semaglutide for insulin sensitivity and weight control, with signals in glucose…

3 days ago

Gastroenterology·Gut

Crohn’s Disease Biomarkers Link Preclinical Onset and Postoperative Recurrence

Shared biomarkers and multiomics signals may connect Crohn’s disease onset with postoperative recurrence, informing prevention and risk stratification.

3 days ago

Gastroenterology·Gut

IBD mouse models reveal conserved inflammatory circuits and gut molecular score

Comparative transcriptomic analysis across 13 IBD mouse models identifies conserved human-relevant inflammatory circuits and a new gut Molecular…

3 days ago

Gastroenterology·Gut

Pancreatic Duct Obstruction and Pain Processing in Pancreatitis

A Gut abstract examines how duct obstruction, altered pain processing, and psychological distress overlap in chronic pancreatic pain…

3 days ago

Gastroenterology·Gut

Deep Learning Could Redefine IBD Biomarker Discovery and Care

A review in IBD examines multimodal deep learning across omics, imaging, and clinical data, with barriers to translation…

3 days ago

Gastroenterology·Gut

Complementary Feeding Timing Not Linked to IBD Risk in Birth Cohorts

A large prospective birth cohort study found no association between timing of complementary food introduction and later inflammatory…

3 days ago

Gastroenterology·Gut

MLCK1 Targeting May Separate ICI Colitis From Antitumour Benefit

Human and mouse data link MLCK1-driven tight junction failure to immune checkpoint inhibitor colitis, while epicatechin preserved antitumour…

3 days ago

Gastroenterology·Nat Rev Onc

Ulcerative colitis trajectories separate vedolizumab response patterns

Patient-reported trajectories in ulcerative colitis split vedolizumab and adalimumab responses into distinct groups and linked one pattern to…

3 days ago

Gastroenterology·DailyMed

Bismuth Subsalicylate Label Expands 5-Symptom Digestive Relief Guidance

DailyMed label details for bismuth subsalicylate caplets outline uses, salicylate cautions, pediatric restrictions, and dosing limits.

3 days ago

Gastroenterology

Digestive disease, hepatology, endoscopy and inflammatory bowel disease.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.