Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

John T. Potts Jr. remembered as an endocrinology pioneer and mentor

John T. Potts Jr. helped define parathyroid hormone biology, modern hyperparathyroidism care, and a generation of endocrine leaders.

By Dr. A. Nikhil Krishnan, MBBS · Oct 27, 2026 · 5 min read

Endocrinology·Nature

THBS1 Emerges as Fibro-Inflammatory Driver in Human Visceral Fat

Single-cell profiling of visceral fat links THBS1 to fibrosis, macrophage activation, impaired adipogenesis, and worsening metabolic traits in…

Oct 27, 2026

Endocrinology·MedCity

Corxel to Go Public as Oral GLP-1 Obesity Drug Nears Phase 3

Corxel Pharmaceuticals is merging with Amanat to fund Phase 3 testing of CX11, an oral GLP-1 obesity drug…

Oct 27, 2026

Endocrinology·BMJ

GLP-1 receptor agonists linked to lower substance use disorder risk in veterans

In a VA cohort, GLP-1 receptor agonists were associated with lower incident substance use disorders and fewer adverse…

Oct 27, 2026

Endocrinology·BMJ Open

GLP-1 and GIP agonists linked to oral adverse effects in scoping review protocol

BMJ Open protocol outlines a scoping review of oral adverse effects linked to GLP-1 and GIP receptor agonists,…

Oct 27, 2026

Endocrinology·Diabetes Care

Amino Acid Profiles May Predict Dysglycemia Risk in Young Adults

BCAMS study suggests childhood amino acid patterns distinguish glycemic phenotypes and may forecast 10-year dysglycemia risk in young…

Oct 27, 2026

Endocrinology·CID

GLP-1/GIP Therapy and Testosterone Aim to Preserve Lean Mass

An Oxford Academic abstract examines whether testosterone can preserve lean mass during GLP-1/GIP-based pharmacotherapy, a key concern in…

Oct 27, 2026

Endocrinology·NLM

Gastric Adenocarcinoma With Osteoblastic Metastases Mimicking Bone Disease

A gastric signet-ring adenocarcinoma presented as high bone turnover with diffuse osteosclerosis, pericardial tamponade, and bone-specific ALP elevation.

Oct 27, 2026

Endocrinology·NLM

Obesity management in primary care gains new pharmacologic options

Primary care is central to obesity prevention and treatment, with GLP-1 therapies, surgery, and early referral reshaping management…

Oct 27, 2026

Endocrinology·DailyMed

Sitagliptin-Metformin Label Strengthens Lactic Acidosis and Renal Warnings

DailyMed updated the sitagliptin-metformin label with boxed lactic acidosis warnings, renal cutoffs, and postmarketing safety signals.

Oct 26, 2026

Endocrinology

Trials, guidelines and clinical evidence across Endocrinology.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.